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Serving leading biopharmaceutical companies globally:

Chubb
Dow
Express Scripts
Medtronic
Healthtrust
McKinsey
US Department of Justice
Daiichi Sankyo
US Army
Baxter

Generated: February 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 9,227,946

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Summary for Patent: 9,227,946
Title:1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1a activity for the treatment of cognitive impairment
Abstract: 1-[2-(2,4-dimethylphenylsulphanyl)phenyl]piperazine exhibits potent activity on SERT, 5-HT.sub.3 and 5-HT.sub.1A and may as such be useful for the treatment of cognitive impairment, especially in depressed patients.
Inventor(s): Faldt; Andre (Ishoj, DK), Holm; Rene (Jyllinge, DK), de Diego; Heidi Lopez (Naerum, DK)
Assignee: H. Lundbeck A/S (Copenhagen-Valby, DK)
Application Number:14/242,337
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 9,227,946

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Takeda Pharms Usa TRINTELLIX vortioxetine hydrobromide TABLET;ORAL 204447-001 Sep 30, 2013 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial METHOD OF TREATING DEPRESSION OR MAJOR DEPRESSIVE DISORDER ➤ Try a Free Trial
Takeda Pharms Usa TRINTELLIX vortioxetine hydrobromide TABLET;ORAL 204447-002 Sep 30, 2013 RX Yes No ➤ Try a Free Trial ➤ Try a Free Trial METHOD OF TREATING DEPRESSION OR MAJOR DEPRESSIVE DISORDER ➤ Try a Free Trial
Takeda Pharms Usa TRINTELLIX vortioxetine hydrobromide TABLET;ORAL 204447-003 Sep 30, 2013 DISCN Yes No ➤ Try a Free Trial ➤ Try a Free Trial METHOD OF TREATING DEPRESSION OR MAJOR DEPRESSIVE DISORDER ➤ Try a Free Trial
Takeda Pharms Usa TRINTELLIX vortioxetine hydrobromide TABLET;ORAL 204447-004 Sep 30, 2013 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial METHOD OF TREATING DEPRESSION OR MAJOR DEPRESSIVE DISORDER ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Foreign Priority and PCT Information for Patent: 9,227,946

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Denmark200600824Jun 16, 2006
Denmark200601223Sep 22, 2006
Denmark200601384Oct 25, 2006
Denmark200700427Mar 20, 2007

Non-Orange Book US Patents Family Members for Patent 9,227,946

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,664,225 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of pain or residual symptoms in depression relating to sleep and cognition ➤ Try a Free Trial
9,095,588 Process for preparing 1-[2-(2,4-dimethylphenysulfanyl)-pheny]piperazine or pharmaceutically acceptable salt thereof ➤ Try a Free Trial
9,101,626 Process for preparing 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine or pharmaceutically acceptable salt thereof ➤ Try a Free Trial
9,125,909 1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT.sub.3 and 5-HT.sub.1A activity for the treatment of cognitive impairment ➤ Try a Free Trial
9,125,910 1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT.sub.3 and 5-HT.sub.1A activity for the treatment of cognitive impairment ➤ Try a Free Trial
9,125,908 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT.sub.3 and 5-HT.sub.1A activity for the treatment of cognitive impairment ➤ Try a Free Trial
8,722,684 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl] piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment ➤ Try a Free Trial
8,969,355 1-[2-(2,4 dimethylphenylsulfanyl)-phenyl]piperazine as a compound with combined serotonin reuptake, 5-HT3 and 5-HT1a activity for the treatment of cognitive impairment ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Patents Family Members for US Patent 9,227,946

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Ukraine 97392 ➤ Try a Free Trial
Ukraine 93250 ➤ Try a Free Trial
Taiwan 200848411 ➤ Try a Free Trial
Taiwan I443091 ➤ Try a Free Trial
Taiwan 200817340 ➤ Try a Free Trial
Tunisia SN08460 ➤ Try a Free Trial
Slovenia 2142193 ➤ Try a Free Trial
Slovenia 2044043 ➤ Try a Free Trial
Serbia 52205 ➤ Try a Free Trial
Serbia 51560 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Merck
Daiichi Sankyo
Queensland Health
Fish and Richardson
Johnson and Johnson
Harvard Business School
US Department of Justice
UBS
McKinsey

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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