Last Updated: August 9, 2026

Details for Patent: 8,975,254


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Which drugs does patent 8,975,254 protect, and when does it expire?

Patent 8,975,254 protects NUBEQA and is included in one NDA.

This patent has eighty patent family members in thirty-seven countries.

Summary for Patent: 8,975,254
Title:Androgen receptor modulating compounds
Abstract:The present disclosure relates to compounds of formula (I), and pharmaceutically acceptable salts thereof. The present disclosure also relates to compositions and methods of treating comprising compounds of formula (I), and pharmaceutically acceptable salts thereof.
Inventor(s):Gerd Wohlfahrt, Olli Törmäkangas, Harri Salo, Iisa Höglund, Arja Karjalainen, Pia Knuuttila, Patrik Holm, Sirpa Rasku, Anniina Vesalainen
Assignee: Orion Oyj
Application Number:US13/504,511
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent landscape, scope, and claims:

error: insufficient information

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Drugs Protected by US Patent 8,975,254

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bayer Healthcare NUBEQA darolutamide TABLET;ORAL 212099-001 Jul 30, 2019 RX Yes Yes 8,975,254 ⤷  Start Trial Y Y TREATMENT OF ADULT PATIENTS WITH NON-METASTATIC CASTRATION RESISTANT PROSTATE CANCER (NMCRPC) ⤷  Start Trial
Bayer Healthcare NUBEQA darolutamide TABLET;ORAL 212099-001 Jul 30, 2019 RX Yes Yes 8,975,254 ⤷  Start Trial Y Y TREATMENT OF ADULT PATIENTS WITH METASTATIC CASTRATION-SENSITIVE PROSTATE CANCER (MCSPC) IN COMBINATION WITH DOCETAXEL ⤷  Start Trial
Bayer Healthcare NUBEQA darolutamide TABLET;ORAL 212099-001 Jul 30, 2019 RX Yes Yes 8,975,254 ⤷  Start Trial Y Y TREATMENT OF ADULT PATIENTS WITH METASTATIC CASTRATION-SENSITIVE PROSTATE CANCER (MCSPC) ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,975,254

PCT Information
PCT FiledOctober 27, 2010PCT Application Number:PCT/FI2010/000065
PCT Publication Date:May 05, 2011PCT Publication Number: WO2011/051540

International Family Members for US Patent 8,975,254

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 2493858 ⤷  Start Trial 301041 Netherlands ⤷  Start Trial
European Patent Office 2493858 ⤷  Start Trial CA 2020 00020 Denmark ⤷  Start Trial
European Patent Office 2493858 ⤷  Start Trial LUC00154 Luxembourg ⤷  Start Trial
European Patent Office 2493858 ⤷  Start Trial PA2020514 Lithuania ⤷  Start Trial
European Patent Office 2493858 ⤷  Start Trial 2020C/514 Belgium ⤷  Start Trial
European Patent Office 2493858 ⤷  Start Trial 122020000030 Germany ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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