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Last Updated: January 20, 2020

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Details for Patent: 8,946,250

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Which drugs does patent 8,946,250 protect, and when does it expire?

Patent 8,946,250 protects BRAFTOVI and is included in one NDA.

This patent has twenty patent family members in eighteen countries.

Summary for Patent: 8,946,250
Title:3,4-diarylpyrazoles as protein kinase inhibitors
Abstract: 3,4-diarylpyrazole derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer. ##STR00001##
Inventor(s): Pulici; Maurizio (Caponago, IT), Zuccotto; Fabio (Milan, IT), Traquandi; Gabriella (Milan, IT), Biondaro; Sonia (Ronca, IT), Trifiro'; Paolo (Genoa, IT), Badari; Alessandra (Vedano al Lambro, IT), Nuvoloni; Stefano (Genoa, IT), Cervi; Giovanni (Como, IT), Marchionni; Chiara (Milan, IT), Modugno; Michele (Cernusco sul Naviglio, IT)
Assignee: Nerviano Medical Sciences S.R.L. (Nerviano (MI), IT)
Application Number:13/970,854
Patent Claim Types:
see list of patent claims
Composition; Compound;

Drugs Protected by US Patent 8,946,250

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Array Biopharma Inc BRAFTOVI encorafenib CAPSULE;ORAL 210496-001 Jun 27, 2018 DISCN Yes No   Start Trial   Start Trial Y Y   Start Trial
Array Biopharma Inc BRAFTOVI encorafenib CAPSULE;ORAL 210496-002 Jun 27, 2018 RX Yes Yes   Start Trial   Start Trial Y Y   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 8,946,250

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
08161076Jul 24, 2008

International Family Members for US Patent 8,946,250

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Austria 557015   Start Trial
Australia 2009273197   Start Trial
Canada 2731146   Start Trial
Chile 2011000124   Start Trial
China 102105459   Start Trial
Cyprus 1117667   Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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Serving leading biopharmaceutical companies globally:

Boehringer Ingelheim
Johnson and Johnson
Merck
Baxter
Express Scripts
Colorcon

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