Last Updated: November 12, 2026

Details for Patent: 8,802,644

Name: Drug Patent Intelligence for US Patent 8802644
Creator: DrugPatentWatch
License: https://www.drugpatentwatch.com/terms.php

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Which drugs does patent 8,802,644 protect, and when does it expire?

Patent 8,802,644 protects ONPATTRO and is included in one NDA.

This patent has seventy-two patent family members in twenty-four countries.

Summary for Patent: 8,802,644

Title:	Lipid formulation
Abstract:	The invention features a cationic lipid of formula I, Also disclosed are targeting lipids, and specific lipid formulations comprising such targeting lipids.
Inventor(s):	Jianxin Chen, Steven Ansell, Akin Akinc, Joseph Robert Dorkin, Xiaojun Qin, William Cantley, Muthiah Manoharan, Kallanthottathil G. Rajeev, Jayaprakash K. Narayanannair, Muthusamy Jayaraman
Assignee:	Arbutus Biopharma Corp
Application Number:	US13/357,856
Patent Litigation and PTAB cases:	See patent lawsuits and PTAB cases for patent 8,802,644
Patent Claim Types: see list of patent claims	Use; Formulation; Delivery; Dosage form;

Drugs Protected by US Patent 8,802,644

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Alnylam Pharms Inc	ONPATTRO	patisiran sodium	SOLUTION;INTRAVENOUS	210922-001	Aug 10, 2018		RX	Yes	Yes	8,802,644	⤷ Start Trial	Y			TREATMENT OF POLYNEUROPATHY OF HEREDITARY TRANSTHYRETIN-MEDIATED AMYLOIDOSIS	⤷ Start Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 8,802,644

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2010259984	⤷ Start Trial
Australia	2017202702	⤷ Start Trial
Australia	2019204984	⤷ Start Trial
Australia	2021201228	⤷ Start Trial
Canada	2764609	⤷ Start Trial
Canada	3014827	⤷ Start Trial
China	102625696	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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