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Serving hundreds of leading biopharmaceutical companies globally:

Argus Health
Cipla
Teva
Healthtrust
QuintilesIMS
Chubb
US Department of Justice
Express Scripts
Cantor Fitzgerald

Generated: April 26, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,754,090

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Summary for Patent: 8,754,090
Title:Use of inhibitors of bruton's tyrosine kinase (Btk)
Abstract: Disclosed herein are methods for treating a cancer comprising: a. administering a Btk inhibitor to a subject sufficient to result in an increase or appearance in the blood of a subpopulation of lymphocytes defined by immunophenotyping; b. determining the expression profile of one or more biomarkers from one or more subpopulation of lymphocytes; and c. administering a second agent based on the determined expression profile.
Inventor(s): Buggy; Joseph J. (Mountain View, CA), Fyfe; Gwen (San Francisco, CA), Loury; David J. (San Jose, CA)
Assignee: Pharmacyclics, Inc. (Sunnyvale, CA)
Application Number:13/340,522
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 8,754,090

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Pharmacyclics Inc IMBRUVICA ibrutinib CAPSULE;ORAL 205552-002 Dec 20, 2017 RX Yes No ➤ Sign Up ➤ Sign Up TREATMENT OF MANTLE CELL LYMPHOMA ➤ Sign Up
Pharmacyclics Inc IMBRUVICA ibrutinib CAPSULE;ORAL 205552-001 Nov 13, 2013 RX Yes Yes ➤ Sign Up ➤ Sign Up TREATMENT OF MANTLE CELL LYMPHOMA ➤ Sign Up
Pharmacyclics Inc IMBRUVICA ibrutinib TABLET;ORAL 210563-001 Feb 16, 2018 RX Yes No ➤ Sign Up ➤ Sign Up TREATMENT OF MANTLE CELL LYMPHOMA ➤ Sign Up
Pharmacyclics Inc IMBRUVICA ibrutinib TABLET;ORAL 210563-002 Feb 16, 2018 RX Yes No ➤ Sign Up ➤ Sign Up TREATMENT OF MANTLE CELL LYMPHOMA ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,754,090

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
9,801,881 Use of inhibitors of bruton's tyrosine kinase (BTK) ➤ Sign Up
9,801,883 Use of inhibitors of bruton's tyrosine kinase (Btk) ➤ Sign Up
8,999,999 Use of inhibitors of Bruton's tyrosine kinase (Btk) ➤ Sign Up
9,814,721 Use of inhibitors of bruton'S tyrosine kinase (BTK) ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Cerilliant
Moodys
QuintilesIMS
Express Scripts
Fish and Richardson
Chinese Patent Office
Julphar
Citi

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