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Serving leading biopharmaceutical companies globally:

Dow
Mallinckrodt
Moodys
Daiichi Sankyo
Novartis
Johnson and Johnson
US Army
Farmers Insurance
Covington
Federal Trade Commission

Generated: December 10, 2017

DrugPatentWatch Database Preview

Details for Patent: 8,703,780

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Which drugs does patent 8,703,780 protect, and when does it expire?


Patent 8,703,780 protects IMBRUVICA and is included in one NDA.

This patent has one hundred and twenty patent family members in twenty-six countries.

Summary for Patent: 8,703,780

Title:Inhibitors of Bruton's tyrosine kinase
Abstract: Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
Inventor(s): Honigberg; Lee (San Francisco, CA), Verner; Erik (Belmont, CA), Pan; Zhengying (Austin, TX)
Assignee: Pharmacyclics, Inc. (Sunnyvale, CA)
Application Number:13/526,161
Patent Claim Types:
see list of patent claims
Use; Device; Delivery;

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Patent Submitted Product Substance Delist Req. Patented / Exclusive Use
Pharmacyclics IncIMBRUVICAibrutinibCAPSULE;ORAL205552-001Nov 13, 2013RXYesYes► Subscribe► Subscribe► SubscribeTREATMENT OF CHRONIC LYMPHOCYTIC LEUKEMIA
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Non-Orange Book Patents for Patent: 8,703,780

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,952,015Inhibitors of Bruton's tyrosine kinase► Subscribe
8,748,438Inhibitors of Bruton's tyrosine kinase► Subscribe
9,181,263Inhibitors of bruton's tyrosine kinase► Subscribe
8,883,435Inhibitors of Bruton's tyrosine kinase► Subscribe
8,476,284Inhibitors of Bruton's tyrosine kinase► Subscribe
8,748,439Inhibitors of Bruton's tyrosine kinase► Subscribe
8,563,563Inhibitors of bruton's tyrosine kinase► Subscribe
9,133,201Inhibitors of Bruton's tyrosine kinase► Subscribe
8,759,516Inhibitors of Bruton's tyrosine kinase► Subscribe
7,514,444Inhibitors of bruton's tyrosine kinase► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: 8,703,780

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
SloveniaEP2530083► Subscribe
SloveniaEP2529621► Subscribe
SloveniaEP2526934► Subscribe
SloveniaEP2526933► Subscribe
SloveniaEP2526771► Subscribe
SloveniaEP2201840► Subscribe
SloveniaEP2081435► Subscribe
Singapore10201508035T► Subscribe
Singapore10201503235V► Subscribe
Singapore166093► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

McKesson
Federal Trade Commission
Farmers Insurance
Boehringer Ingelheim
AstraZeneca
Healthtrust
Deloitte
UBS
Covington
QuintilesIMS

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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