Upgrade to enjoy subscriber-only features like email alerts and data export. See the Plans and Pricing

Serving leading biopharmaceutical companies globally:

Fuji
Cipla
Deloitte
AstraZeneca
US Army
Citi
Express Scripts
UBS
Harvard Business School
Novartis

Generated: February 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,480,631

« Back to Dashboard

Which drugs does patent 8,480,631 protect, and when does it expire?

Patent 8,480,631 protects OTREXUP and is included in one NDA.

This patent has twelve patent family members in seven countries.
Summary for Patent: 8,480,631
Title:Hazardous agent injection system
Abstract: A hazardous agent injection system including from about 0.02 ml to about 4.0 ml of methotrexate at a concentration of from about 7.5 mg/ml to about 150 mg/ml; a needle-assisted jet injector including a container configured to contain the methotrexate; a injection outlet member associated with the container; an injection-assisting needle coupled to the injection outlet member; a firing mechanism associated with the container; an energy source associated with the firing mechanism; and a trigger mechanism associated with the firing mechanism, wherein the needle-assisted jet injector is configured to eject the methotrexate from the injection outlet member such that the C.sub.max, T.sub.max and bioavailability of the needle-assisted jet injected methotrexate falls between about 80% and about 125% of the C.sub.max, T.sub.max and bioavailability of methotrexate delivered by a hand-powered syringe.
Inventor(s): Wotton; Paul (Stamford, CT), Sadowsky; Peter L. (Woodbury, MN), Hayes; John William (Chaska, MN)
Assignee: Antares Pharma, Inc. (Ewing, NJ)
Application Number:13/607,659
Patent Claim Types:
see list of patent claims
Dosage form; Use;

Drugs Protected by US Patent 8,480,631

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-005 Nov 7, 2014 DISCN Yes No ➤ Try a Free Trial ➤ Try a Free Trial Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Try a Free Trial
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-001 Oct 11, 2013 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Try a Free Trial
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-006 Mar 24, 2016 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Try a Free Trial
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-002 Oct 11, 2013 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Try a Free Trial
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-007 Mar 24, 2016 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Try a Free Trial
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-003 Oct 11, 2013 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Try a Free Trial
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-008 Mar 24, 2016 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Try a Free Trial
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-004 Oct 11, 2013 RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

Non-Orange Book US Patents Family Members for Patent 8,480,631

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,579,865 Hazardous agent injection system ➤ Try a Free Trial
9,750,881 Hazardous agent injection system ➤ Try a Free Trial
8,945,063 Hazardous agent injection system ➤ Try a Free Trial
9,421,333 Hazardous agent injection system ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

International Patents Family Members for US Patent 8,480,631

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
South Korea 101597672 ➤ Try a Free Trial
South Korea 20120028294 ➤ Try a Free Trial
Japan 2016104214 ➤ Try a Free Trial
Japan 5968976 ➤ Try a Free Trial
Japan 2015042270 ➤ Try a Free Trial
Japan 5732039 ➤ Try a Free Trial
Japan 2012521224 ➤ Try a Free Trial
European Patent Office 2408493 ➤ Try a Free Trial
China 102612381 ➤ Try a Free Trial
Canada 2755779 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

This preview shows a limited data set. Subscribe for full access, or try a Free Trial

For more information try a trial or see the plans and pricing

Serving hundreds of leading biopharmaceutical companies globally:

Cantor Fitzgerald
Merck
Johnson and Johnson
Fish and Richardson
Chinese Patent Office
Baxter
US Army
Accenture
Farmers Insurance

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

botpot