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Serving hundreds of leading biopharmaceutical companies globally:

Moodys
Covington
Daiichi Sankyo
UBS
McKesson
Colorcon
Baxter
Mallinckrodt
QuintilesIMS

Generated: April 24, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,480,631

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Which drugs does patent 8,480,631 protect, and when does it expire?

Patent 8,480,631 protects OTREXUP and is included in one NDA.

This patent has twelve patent family members in seven countries.
Summary for Patent: 8,480,631
Title:Hazardous agent injection system
Abstract: A hazardous agent injection system including from about 0.02 ml to about 4.0 ml of methotrexate at a concentration of from about 7.5 mg/ml to about 150 mg/ml; a needle-assisted jet injector including a container configured to contain the methotrexate; a injection outlet member associated with the container; an injection-assisting needle coupled to the injection outlet member; a firing mechanism associated with the container; an energy source associated with the firing mechanism; and a trigger mechanism associated with the firing mechanism, wherein the needle-assisted jet injector is configured to eject the methotrexate from the injection outlet member such that the C.sub.max, T.sub.max and bioavailability of the needle-assisted jet injected methotrexate falls between about 80% and about 125% of the C.sub.max, T.sub.max and bioavailability of methotrexate delivered by a hand-powered syringe.
Inventor(s): Wotton; Paul (Stamford, CT), Sadowsky; Peter L. (Woodbury, MN), Hayes; John William (Chaska, MN)
Assignee: Antares Pharma, Inc. (Ewing, NJ)
Application Number:13/607,659
Patent Claim Types:
see list of patent claims
Dosage form; Use;

Drugs Protected by US Patent 8,480,631

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-005 Nov 7, 2014 DISCN Yes No ➤ Sign Up ➤ Sign Up Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Sign Up
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-001 Oct 11, 2013 RX Yes Yes ➤ Sign Up ➤ Sign Up Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Sign Up
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-006 Mar 24, 2016 RX Yes Yes ➤ Sign Up ➤ Sign Up Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Sign Up
Antares Pharma Inc OTREXUP methotrexate SOLUTION;SUBCUTANEOUS 204824-002 Oct 11, 2013 RX Yes Yes ➤ Sign Up ➤ Sign Up Y SUBCUTANEOUS INJECTION OF METHOTREXATE ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,480,631

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
9,421,333 Hazardous agent injection system ➤ Sign Up
9,750,881 Hazardous agent injection system ➤ Sign Up
8,579,865 Hazardous agent injection system ➤ Sign Up
8,945,063 Hazardous agent injection system ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

McKinsey
Daiichi Sankyo
Colorcon
Cerilliant
Federal Trade Commission
Julphar
AstraZeneca
Accenture
Harvard Business School

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