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Serving hundreds of leading biopharmaceutical companies globally:

Medtronic
AstraZeneca
Boehringer Ingelheim
UBS
Accenture
Dow
Healthtrust
McKinsey
Queensland Health

Generated: April 20, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,450,372

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Which drugs does patent 8,450,372 protect, and when does it expire?

Patent 8,450,372 protects ZOLINZA and is included in one NDA.

This patent has forty-two patent family members in twenty-four countries.
Summary for Patent: 8,450,372
Title:Formulations of suberoylanilide hydroxamic acid and methods for producing same
Abstract: The present invention provides a pharmaceutical composition or crystalline composition with a specific dissolution profile, which comprises suberoylanilide hydroxamic acid or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. The present invention provides a process of producing said crystalline composition or pharmaceutical composition. The present invention also provides compositions with a specific particle size distribution.
Inventor(s): Wong; Jeannie Chow (Chicago, IL), Cote; Aaron S. (West Windsor, NJ), Dienemann; Erik A. (Metuchen, NJ), Gallagher; Kimberly (Green Lane, PA), Ikeda; Craig (Harleysville, PA), Moser; Justin (Collegeville, PA), Rajniak; Pavol (Lansdale, PA), Reed; Robert A. (Line Lexington, PA), Starbuck; Cindy (Branchburg, NJ), Tung; Hsien-Hsin (Edison, NJ), Wang; Qingxi (Ambler, PA), Cohen; Benjamin Max (Cranford, NJ), Capodanno; Vincent R. (Hillsborough, NJ), Sell; Brian (Royersford, PA), Miller; Thomas A. (Wakefield, MA)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:12/686,843
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation; Dosage form; Process;

Drugs Protected by US Patent 8,450,372

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Merck ZOLINZA vorinostat CAPSULE;ORAL 021991-001 Oct 6, 2006 RX Yes Yes ➤ Sign Up ➤ Sign Up TREATMENT OF CUTANEOUS MANIFESTATIONS IN PATIENTS WTIH CUTANEOUS T-CELL LYMPHOMA (CTCL) ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,450,372

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,093,295 Formulations of suberoylanilide hydroxamic acid and methods for producing the same ➤ Sign Up
8,288,440 Formulations of suberoylanilide hydroxamic acid and methods for producing same ➤ Sign Up
Patent No. Title Estimated Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Moodys
Daiichi Sankyo
Boehringer Ingelheim
Cerilliant
Fuji
Express Scripts
McKesson
Federal Trade Commission
Colorcon

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