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Serving hundreds of leading biopharmaceutical companies globally:

Fuji
Express Scripts
Cerilliant
McKinsey
Merck
Federal Trade Commission
US Army
Covington
Fish and Richardson

Generated: June 22, 2018

DrugPatentWatch Database Preview

Details for Patent: 8,246,989

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Summary for Patent: 8,246,989
Title:Dosage forms of bisphosphonates
Abstract: Oral dosage forms of a bisphosphonate comprised of a safe and effective amount of a pharmaceutical composition comprising a bisphosphonate, a chelating agent, and, means for effecting delayed release of the bisphosphonate and the chelating agent in the lower gastrointestinal tract provide delivery of the pharmaceutical composition to the lower gastrointestinal tract of the mammal subject and pharmaceutically effective absorption of the bisphosphonate with or without food or beverages. The present invention substantially alleviates the interaction between bisphosphonates and food or beverages, which interaction results in the bisphosphonate active ingredient not being available for absorption. The resulting oral dosage form may thus be taken with or without food. Further, the present invention effects delivery of the bisphosphonate and the chelating agent to the lower GI tract, substantially alleviating the upper GI irritation associated with bisphosphonate therapies. These benefits simplify previously complex treatment regimens and can lead to increased patient compliance with bisphosphonate therapies.
Inventor(s): Dansereau; Richard John (Cincinnati, OH), Burgio, Jr.; David Ernest (Liberty Township, OH)
Assignee: Warner Chilcott Company, LLC (Fajardo, PR)
Application Number:12/637,100
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 8,246,989
Patent Claim Types:
see list of patent claims
Compound; Dosage form; Formulation;

Drugs Protected by US Patent 8,246,989

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted
Apil ATELVIA risedronate sodium TABLET, DELAYED RELEASE;ORAL 022560-001 Oct 8, 2010 AB RX Yes Yes ➤ Try a Free Trial ➤ Try a Free Trial Y ➤ Try a Free Trial
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Patent Submitted

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Non-Orange Book US Patents Family Members for Patent 8,246,989

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,409,615 Low dosage forms of risedronate or its salts ➤ Try a Free Trial
7,645,459 Dosage forms of bisphosphonates ➤ Try a Free Trial
8,535,718 Dosage forms of bisphosphonates ➤ Try a Free Trial
8,409,614 Low dosage forms of risedronate or its salts ➤ Try a Free Trial
Patent No. Title Estimated Patent Expiration

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International Family Members for US Patent 8,246,989

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Taiwan 201138783 ➤ Try a Free Trial
Taiwan I351285 ➤ Try a Free Trial
Taiwan 200607514 ➤ Try a Free Trial
San Marino AP200700047 ➤ Try a Free Trial
Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Fish and Richardson
Citi
Chubb
Baxter
McKinsey
Merck
Farmers Insurance
Fuji
QuintilesIMS

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