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Last Updated: October 21, 2020

DrugPatentWatch Database Preview

Details for Patent: 8,158,601

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Which drugs does patent 8,158,601 protect, and when does it expire?

Patent 8,158,601 protects ONPATTRO and is included in one NDA.

This patent has fifty-three patent family members in twenty-three countries.

Summary for Patent: 8,158,601
Title:Lipid formulation
Abstract: The invention features a cationic lipid of formula I, ##STR00001## an improved lipid formulation comprising a cationic lipid of formula I and corresponding methods of use. Also disclosed are targeting lipids, and specific lipid formulations comprising such targeting lipids.
Inventor(s): Chen; Jianxin (Cambridge, MA), Ansell; Steven (Cambridge, MA), Akinc; Akin (Cambridge, MA), Dorkin; Joseph Robert (Cambridge, MA), Qin; Xiaojun (Cambridge, MA), Cantley; William (Cambridge, MA), Manoharan; Muthiah (Cambridge, MA), Rajeev; Kallanthottathil G. (Cambridge, MA), Narayanannair; Jayaprakash K. (Cambridge, MA), Jayaraman; Muthusamy (Cambridge, MA)
Assignee: Alnylam Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:12/813,448
Patent Claim Types:
see list of patent claims
Use; Formulation; Compound; Delivery;

Drugs Protected by US Patent 8,158,601

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Alnylam Pharms Inc ONPATTRO patisiran sodium SOLUTION;INTRAVENOUS 210922-001 Aug 10, 2018 RX Yes Yes   Start Trial   Start Trial Y TREATMENT OF POLYNEUROPATHY OF HEREDITARY TRANSTHYRETIN-MEDIATED AMYLOIDOSIS   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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Serving leading biopharmaceutical companies globally:

Moodys
McKinsey
Mallinckrodt
AstraZeneca
Johnson and Johnson
Colorcon

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