DrugPatentWatch Database Preview
Details for Patent: 8,012,976
» See Plans and Pricing
Which drugs does patent 8,012,976 protect, and when does it expire?
Patent 8,012,976 protects TALZENNA and is included in one NDA.
This patent has fifty patent family members in twenty-eight countries.
Summary for Patent: 8,012,976
Title: | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) |
Abstract: | A compound having the structure set forth in Formula (I) and Formula (II): ##STR00001## wherein the substituents Y, Z, A, B, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity. |
Inventor(s): | Wang; Bing (San Jose, CA), Chu; Daniel (Santa Clara, CA) |
Assignee: | BioMarin Pharmaceutical Inc. (Novato, CA) |
Application Number: | 12/510,096 |
Patent Claim Types: see list of patent claims | Composition; Compound; |
Drugs Protected by US Patent 8,012,976
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pfizer | TALZENNA | talazoparib tosylate | CAPSULE;ORAL | 211651-001 | Oct 16, 2018 | RX | Yes | No | Start Trial | Start Trial | Y | Y | Start Trial | |||
Pfizer | TALZENNA | talazoparib tosylate | CAPSULE;ORAL | 211651-002 | Oct 16, 2018 | RX | Yes | Yes | Start Trial | Start Trial | Y | Y | Start Trial | |||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,012,976
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Argentina | 072970 | Start Trial | |||
Australia | 2009279944 | Start Trial | |||
Brazil | PI0917119 | Start Trial | |||
Canada | 2732797 | Start Trial | |||
China | 102171214 | Start Trial | |||
China | 103896942 | Start Trial | |||
China | 104478875 | Start Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |