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Details for Patent: 8,012,976
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See Plans and PricingWhich drugs does patent 8,012,976 protect, and when does it expire?
Patent 8,012,976 protects TALZENNA and is included in one NDA.
This patent has forty-seven patent family members in twenty-seven countries.
Summary for Patent: 8,012,976
| Title: | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) |
| Abstract: | A compound having the structure set forth in Formula (I) and Formula (II): ##STR00001## wherein the substituents Y, Z, A, B, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as defined herein. Provided herein are inhibitors of poly(ADP-ribose)polymerase activity. Also described herein are pharmaceutical compositions that include at least one compound described herein and the use of a compound or pharmaceutical composition described herein to treat diseases, disorders and conditions that are ameliorated by the inhibition of PARP activity. |
| Inventor(s): | Wang; Bing (San Jose, CA), Chu; Daniel (Santa Clara, CA) |
| Assignee: | BioMarin Pharmaceutical Inc. (Novato, CA) |
| Application Number: | 12/510,096 |
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Patent Claim Types: see list of patent claims | Composition; Compound; |
Drugs Protected by US Patent 8,012,976
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pfizer Inc | TALZENNA | talazoparib tosylate | CAPSULE;ORAL | 211651-001 | Oct 16, 2018 | RX | Yes | No | Start Trial | Start Trial | Y | Y | Start Trial | |||
| Pfizer Inc | TALZENNA | talazoparib tosylate | CAPSULE;ORAL | 211651-002 | Oct 16, 2018 | RX | Yes | Yes | Start Trial | Start Trial | Y | Y | Start Trial | |||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,012,976
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Argentina | 072970 | Start Trial | |||
| Australia | 2009279944 | Start Trial | |||
| Brazil | PI0917119 | Start Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
