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Serving leading biopharmaceutical companies globally:

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Daiichi Sankyo
Accenture
Mallinckrodt

Generated: November 21, 2017

DrugPatentWatch Database Preview

Details for Patent: 7,737,112

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Which drugs does patent 7,737,112 protect, and when does it expire?


Patent 7,737,112 protects KYPROLIS and is included in one NDA. There has been one Paragraph IV challenge on Kyprolis.

This patent has fifty-four patent family members in twenty countries.

Summary for Patent: 7,737,112

Title:Composition for enzyme inhibition
Abstract: Compositions comprising one or more practically insoluble proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin, substantially increase the solubility of these proteasome inhibitors and facilitate their administration. Such compositions optionally comprise a buffer. Methods of treatment using such compositions are also disclosed.
Inventor(s): Lewis; Evan R. (Pacifica, CA), Ho; Mark Nguyen (San Jose, CA), Fonseca; Fabiana N. (New York, NY)
Assignee: Onyx Therapeutics, Inc. (South San Francisco, CA)
Application Number:11/299,265
Patent Claim Types:
see list of patent claims
Composition; Formulation; Compound;

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Onyx Therap
KYPROLIS
carfilzomib
POWDER;INTRAVENOUS202714-002Jun 3, 2016RXYesNo► Subscribe► SubscribeY
Onyx Therap
KYPROLIS
carfilzomib
POWDER;INTRAVENOUS202714-001Jul 20, 2012RXYesYes► Subscribe► SubscribeY
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Non-Orange Book Patents for Patent: 7,737,112

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
8,088,741Compounds for enzyme inhibition► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Because of the complexity of determining patent expiration dates it is advisable to have patent counsel verify freedom to operate.

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International Patent Family for Patent: 7,737,112

Country Document Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Canada2566839► Subscribe
Canada2589921► Subscribe
China101014612► Subscribe
China101180071► Subscribe
China102847136► Subscribe
China102875642► Subscribe
Cyprus1111489► Subscribe
Cyprus1114025► Subscribe
Cyprus1115605► Subscribe
Spain2510840► Subscribe
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The estimated expiration dates shown above are derived by simply adding 20 years to the priority date.
Due to the complexity of determining patent expirations even in a single country, compounded by the diversity of global patent laws, it is advisable to have patent counsel verify freedom to operate.

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Serving leading biopharmaceutical companies globally:

Daiichi Sankyo
Deloitte
Johnson and Johnson
Accenture
UBS
McKinsey
Cipla
Fuji
Harvard Business School
Covington

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.

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