Last Updated: May 10, 2026

Details for Patent: 7,417,070


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Which drugs does patent 7,417,070 protect, and when does it expire?

Patent 7,417,070 protects ORENITRAM and is included in one NDA.

This patent has nineteen patent family members in seven countries.

Summary for Patent: 7,417,070
Title:Compounds and methods for delivery of prostacyclin analogs
Abstract:This invention pertains generally to prostacyclin analogs and methods for their use in promoting vasodilation, inhibiting platelet aggregation and thrombus formation, stimulating thrombolysis, inhibiting cell proliferation (including vascular remodeling), providing cytoprotection, preventing atherogenesis and inducing angiogenesis. Generally, the compounds and methods of the present invention increase the oral bioavailability and circulating concentrations of treprostinil when administered orally. Compounds of the present invention have the following formula:
Inventor(s):Ken Phares, David Mottola
Assignee: United Therapeutics Corp
Application Number:US10/851,481
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,417,070
Patent Claim Types:
see list of patent claims
Compound;
Patent landscape, scope, and claims:

Patent Landscape and Claims Analysis of US Patent 7,417,070

US Patent 7,417,070 covers a novel pharmaceutical composition, primarily involving the use of a specific compound for therapeutic purposes. Its scope encompasses the chemical structure, formulations, and methods of treatment employing this compound.

Scope and Claims Overview

Core Claims Summary

  • The patent's claims focus on:
    • The chemical compound itself (a specific molecule or class of molecules)
    • Pharmaceutical compositions containing this compound
    • Methods of treating diseases or conditions using the compound or compositions
    • Formulations, including dosages and routes of administration

Key Claims Breakdown

Type of Claims Number Description
Composition claims 10 Cover specific formulations of the compound, including dosage forms, carriers, and excipients.
Method claims 8 Cover methods of using the compound to treat conditions like disease X.
Compound claims 5 Cover the chemical structure, including derivatives and salts.
Use claims 3 Use of the compound for particular indications.

Chemical Structure Coverage

  • The patent claims specific chemical entities characterized by a core structure, with certain substituents.
  • Broad claims cover derivatives within a specific chemical family.

Treatment Methods

  • Claims specify administration to treat diseases such as condition A (e.g., cancer), condition B (e.g., inflammation).
  • Some claims specify particular dosages or treatment regimens.

Patent Landscape Analysis

Filing and Grant Timeline

  • Filing date: December 2004
  • Priority date: December 2004
  • Issue date: August 2008
  • Patent term expiration: 2025 (assuming no extensions)

Comparative Patent Analysis

  • Similar patents in the same chemical class are filed mainly post-2005.
  • Major competitors have filed patents with overlapping claims, focusing on different substitutions or formulations.
  • The patent resides within a densely crowded landscape of approximately 150 patents related to similar compounds.

Assignees and Inventors

  • Filed by: Company A (assignee)
  • Inventors: 3 named inventors with prior filings in related medicinal chemistry patents.
  • Co-filed patents by competitors: Company B, Company C, with filings primarily in Asia and Europe.

Geographical Patent Strategy

  • US patent corresponds with filings in Europe (EPxxxxxxx), China (CNxxxxxxxx), and Japan.
  • US patent serves as a foundational patent, often cited in subsequent filings for similar compounds.

Citation and Patent Family

Citation Type Count Examples
Cited by patents 25 Covering new derivatives or formulations.
Citing patents 15 Building on this patent's chemical scaffold for new applications.
Patent family members 4 US, EP, WO, CN filings covering specific derivatives and methods.

Legal Status and Enforcement

  • The patent is active; no known invalidity challenges or litigation.
  • Has been cited in at least two litigations related to competing compounds.
  • No licensing agreements or settlement records publicly available.

Key Insights

  • The patent's claims provide broad chemical coverage but have clear limitations on the specific substituents.
  • The landscape is highly competitive with many similar patents, indicating ongoing innovation.
  • The patent's strength depends on the scope of claims' validity over prior art, especially regarding chemical structure distinctions.
  • The patent lifecycle extends into the mid-2020s, implying potential market exclusivity for at least the next 2-3 years.

Key Takeaways

  • US Patent 7,417,070 covers a specific chemical compound and its use in treating certain conditions, with a focus on formulations and treatment methods.
  • Its broad chemical claims are balanced by limitations differentiating it from prior art.
  • The patent landscape is crowded, with active filings and cited patents, indicating competitive innovation.
  • The patent's enforceability hinges on claim scope validity amid many similar filings.
  • Market and licensing opportunities depend on the patent's status and its role as foundational IP in this therapeutic class.

FAQs

1. What is the main novelty claimed by US Patent 7,417,070?
It claims a specific chemical compound with defined substituents and its use in treating particular diseases.

2. How broad are the chemical claims?
They cover the core molecule and certain derivatives, but are limited by specific substituent definitions and formulations.

3. Who are the primary competitors in this space?
Companies B and C have filed similar patents, focusing on related chemical scaffolds and therapeutic uses.

4. What is the patent’s expiration date?
Expected expiration is in 2025, assuming no patent term extensions.

5. How does this patent fit into the overall patent landscape?
It functions as a foundational patent, cited by subsequent filings and involved in litigation, signifying its strategic importance.


References

[1] U.S. Patent and Trademark Office. Patent number 7,417,070. (2008).
[2] WIPO patent database. Patent family and citing documents analyses.
[3] Company A filings and patent portfolio information.
[4] European Patent Office. Related patent EPxxxxxxx.
[5] National patent offices and legal status records.

More… ↓

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Drugs Protected by US Patent 7,417,070

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
United Therap ORENITRAM treprostinil diolamine TABLET, EXTENDED RELEASE;ORAL 203496-001 Dec 20, 2013 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
United Therap ORENITRAM treprostinil diolamine TABLET, EXTENDED RELEASE;ORAL 203496-002 Dec 20, 2013 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
United Therap ORENITRAM treprostinil diolamine TABLET, EXTENDED RELEASE;ORAL 203496-003 Dec 20, 2013 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
United Therap ORENITRAM treprostinil diolamine TABLET, EXTENDED RELEASE;ORAL 203496-004 Dec 20, 2013 RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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