Last Updated: August 9, 2026

Details for Patent: 7,094,781


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Which drugs does patent 7,094,781 protect, and when does it expire?

Patent 7,094,781 protects OPSUMIT and OPSYNVI and is included in two NDAs.

Protection for OPSUMIT has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has thirty-one patent family members in twenty-three countries.

Summary for Patent: 7,094,781
Title:Sulfamides and their use as endothelin receptor antagonists
Abstract:The invention relates to novel sulfamides and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists.
Inventor(s):Martin Bolli, Christoph Boss, Walter Fischli, Martine Clozel, Thomas Weller
Assignee: Actelion Pharmaceuticals Ltd
Application Number:US10/433,041
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 7,094,781
Patent Claim Types:
see list of patent claims
Compound;

Drugs Protected by US Patent 7,094,781

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Actelion OPSUMIT macitentan TABLET;ORAL 204410-001 Oct 18, 2013 AB RX Yes Yes 7,094,781*PED ⤷  Start Trial Y ⤷  Start Trial
Actelion OPSYNVI macitentan; tadalafil TABLET;ORAL 218490-001 Mar 22, 2024 RX Yes No 7,094,781*PED ⤷  Start Trial Y ⤷  Start Trial
Actelion OPSYNVI macitentan; tadalafil TABLET;ORAL 218490-002 Mar 22, 2024 RX Yes Yes 7,094,781*PED ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 7,094,781

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
PCT/EP00/12890Dec 18, 2000
PCT Information
PCT FiledDecember 04, 2001PCT Application Number:PCT/EP01/14182
PCT Publication Date:July 11, 2002PCT Publication Number: WO02/053557

International Family Members for US Patent 7,094,781

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1345920 ⤷  Start Trial CA 2014 00012 Denmark ⤷  Start Trial
European Patent Office 1345920 ⤷  Start Trial 92381 Luxembourg ⤷  Start Trial
European Patent Office 1345920 ⤷  Start Trial C300672 Netherlands ⤷  Start Trial
European Patent Office 1345920 ⤷  Start Trial 14C0017 France ⤷  Start Trial
European Patent Office 1345920 ⤷  Start Trial 1490025-2 Sweden ⤷  Start Trial
European Patent Office 1345920 ⤷  Start Trial C01345920/01 Switzerland ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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