Last Updated: November 9, 2026

Details for Patent: 6,967,208

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Which drugs does patent 6,967,208 protect, and when does it expire?

Patent 6,967,208 protects ELIQUIS SPRINKLE and ELIQUIS and is included in two NDAs.

Protection for ELIQUIS SPRINKLE has been extended six months for pediatric studies, as indicated by the *PED designation in the table below.

This patent has seventy-four patent family members in thirty-six countries.

Summary for Patent: 6,967,208
Title:Lactam-containing compounds and derivatives thereof as factor Xa inhibitors
Abstract:The present application describes lactam-containing compounds and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein ring P, if present is a 5-7 membered carbocycle or heterocycle and ring M is a 5-7 membered carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
Inventor(s):Donald J. P. Pinto, Mimi L. Quan, Michael J. Orwat, Yun-Long Li, Wei Han, Jennifer X. Qiao, Patrick Y. S. Lam, Stephanie L. Koch
Assignee: Bristol Myers Squibb Co
Application Number:US10/245,122
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 6,967,208
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 6,967,208

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bristol ELIQUIS SPRINKLE apixaban FOR SUSPENSION;ORAL 220073-001 Apr 17, 2025 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Bristol Myers Squibb ELIQUIS apixaban TABLET, FOR SUSPENSION;ORAL 202155-003 Apr 17, 2025 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Bristol Myers Squibb ELIQUIS apixaban TABLET;ORAL 202155-001 Dec 28, 2012 AB RX Yes No ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
Bristol Myers Squibb ELIQUIS apixaban TABLET;ORAL 202155-002 Dec 28, 2012 AB RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 6,967,208

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 1427415 ⤷  Start Trial C300500 Netherlands ⤷  Start Trial
European Patent Office 1427415 ⤷  Start Trial C20110017 00045 Estonia ⤷  Start Trial
European Patent Office 1427415 ⤷  Start Trial CA 2011 00028 Denmark ⤷  Start Trial
European Patent Office 1427415 ⤷  Start Trial 91888 Luxembourg ⤷  Start Trial
European Patent Office 1427415 ⤷  Start Trial 1190029-7 Sweden ⤷  Start Trial
European Patent Office 1427415 ⤷  Start Trial PA2011012 Lithuania ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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