Last Updated: November 9, 2026

Details for Patent: 12,514,857

Name: Drug Patent Intelligence for US Patent 12514857
Creator: DrugPatentWatch
License: https://www.drugpatentwatch.com/terms.php

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Which drugs does patent 12,514,857 protect, and when does it expire?

Patent 12,514,857 protects LUMIFY and LUMIFY PRESERVATIVE FREE and is included in two NDAs.

This patent has thirty-seven patent family members in sixteen countries.

Summary for Patent: 12,514,857

Title:	Vasoconstriction compositions and methods of use
Abstract:	The invention generally relates to compositions for inducing vasoconstriction. The compositions comprise highly selective alpha-2 adrenergic receptor agonists, at low concentrations, such as below 0.05% weight by volume. The compositions preferably comprise brimonidine. The compositions preferably have pH from about 4.0 to about 7.5.
Inventor(s):	Gerald Horn
Assignee:	Eye Therapies LLC
Application Number:	US18/643,253
Patent Claim Types: see list of patent claims	Use; Composition;

Drugs Protected by US Patent 12,514,857

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Bausch And Lomb Inc	LUMIFY	brimonidine tartrate	SOLUTION/DROPS;OPHTHALMIC	208144-001	Dec 22, 2017		OTC	Yes	Yes	12,514,857	⤷ Start Trial				RELIEVES REDNESS OF THE EYE DUE TO MINOR EYE IRRITATIONS	⤷ Start Trial
Bausch And Lomb Inc	LUMIFY PRESERVATIVE FREE	brimonidine tartrate	SOLUTION/DROPS;OPHTHALMIC	218424-001	Apr 19, 2024		OTC	Yes	Yes	12,514,857	⤷ Start Trial				RELIEVES REDNESS OF THE EYE DUE TO MINOR EYE IRRITATIONS	⤷ Start Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 12,514,857

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Brazil	112016004054	⤷ Start Trial
Canada	2732521	⤷ Start Trial
Canada	2782817	⤷ Start Trial
Canada	2832953	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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