Last Updated: September 24, 2026

Details for Patent: 12,280,025


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Which drugs does patent 12,280,025 protect, and when does it expire?

Patent 12,280,025 protects LODOCO and is included in one NDA.

This patent has forty-eight patent family members in twenty-four countries.

Summary for Patent: 12,280,025
Title:Treatment or prevention of cardiovascular events via the administration of a colchicine derivative
Abstract:A method for reducing a composite endpoint risk of myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death in a subject including administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the patient has at least one history of diabetes, a past myocardial infarction, an unstable angina, a coronary bypass surgery, and a coronary angioplasty; wherein the patient is also administered a daily dose of statin therapy; and wherein the composite endpoint risk in the subject is reduced relative to a dosing regimen where the patient receives standard secondary prevention therapy of a statin.
Inventor(s):Mark Nidorf
Assignee: Murray and Poole Enterprises Ltd
Application Number:US18/367,412
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 12,280,025
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation; Delivery; Dosage form;

Drugs Protected by US Patent 12,280,025

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Agepha Pharma Fz LODOCO colchicine TABLET;ORAL 215727-001 Jun 16, 2023 RX Yes Yes 12,280,025 ⤷  Start Trial A METHOD FOR REDUCING A RISK OF AT LEAST ONE CARDIOVASCULAR EVENT ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 12,280,025

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Australia 2013337605 ⤷  Start Trial
Australia 2018203715 ⤷  Start Trial
Australia 2019232879 ⤷  Start Trial
Australia 2021282491 ⤷  Start Trial
Australia 2024205084 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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