Last Updated: November 12, 2026

Details for Patent: 12,251,365

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Which drugs does patent 12,251,365 protect, and when does it expire?

Patent 12,251,365 protects VYALEV and is included in one NDA.

This patent has eighteen patent family members in fourteen countries.

Summary for Patent: 12,251,365
Title:Pharmaceutical formulations for subcutaneous administration
Abstract:The present disclosure relates to compositions of levodopa 4′-monophosphate and carbidopa 4′-monophosphate having a weight by weight ratio of about 20:1 and methods of treating Parkinson's disease and associated conditions by subcutaneous administration of such compositions.
Inventor(s):Ehab Moussa, Matthew Rosebraugh, Feroz Jameel, Nancy Sever, Maurizio F. Facheris, Weining Z Robieson, Charles S. Locke, Sven Stodtmann
Assignee: AbbVie Inc
Application Number:US16/684,874
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 12,251,365

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Abbvie VYALEV foscarbidopa; foslevodopa SOLUTION;SUBCUTANEOUS 216962-001 Oct 16, 2024 RX Yes Yes 12,251,365 ⤷  Start Trial TREATMENT OF MOTOR FLUCTUATIONS IN ADULTS WITH ADVANCED PARKINSON'S DISEASE ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 12,251,365

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
Argentina 117097 ⤷  Start Trial
Australia 2019379806 ⤷  Start Trial
Australia 2025256148 ⤷  Start Trial
Brazil 112021009353 ⤷  Start Trial
Canada 3117983 ⤷  Start Trial
China 113015531 ⤷  Start Trial
European Patent Office 3880210 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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