Last Updated: October 26, 2026

Details for Patent: 12,059,449

Name: Drug Patent Intelligence for US Patent 12059449
Creator: DrugPatentWatch
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Which drugs does patent 12,059,449 protect, and when does it expire?

Patent 12,059,449 protects VEVYE and is included in one NDA.

This patent has fifteen patent family members in eleven countries.

Summary for Patent: 12,059,449

Title:	Ophthalmic composition for treatment of dry eye disease
Abstract:	The invention provides ophthalmic compositions comprising about 0.1% (w/v) cyclosporine dissolved in 1-(perfluorobutyl)pentane for use in the topical treatment of dry eye disease and provides for treatment methods thereof. The invention further provides kits comprising such compositions.
Inventor(s):	Chiara Silvana Leo, Sonja KRÖSSER, Thomas Schlüter, Alice MEIDES
Assignee:	Novaliq GmbH
Application Number:	US17/711,932
Patent Claim Types: see list of patent claims	Use; Composition; Formulation;

Drugs Protected by US Patent 12,059,449

Glossary

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Harrow Eye	VEVYE	cyclosporine	SOLUTION;OPHTHALMIC	217469-001	May 30, 2023		RX	Yes	Yes	12,059,449	⤷ Start Trial	Y			INCREASE TEAR PRODUCTION IN PATIENTS WITH KERATOCONJUNCTIVITIS SICCA (DRY EYE).	⤷ Start Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

International Family Members for US Patent 12,059,449

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2019358249	⤷ Start Trial
Canada	3112031	⤷ Start Trial
China	112823020	⤷ Start Trial
European Patent Office	3863658	⤷ Start Trial
European Patent Office	4406533	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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