Last Updated: July 14, 2026

Details for Patent: 11,925,620


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Which drugs does patent 11,925,620 protect, and when does it expire?

Patent 11,925,620 protects OGSIVEO and is included in one NDA.

This patent has seventy-five patent family members in twenty-six countries.

Summary for Patent: 11,925,620
Title:Treatments with nirogacestat
Abstract:The present disclosure relates to improved methods of treatment with nirogacestat.
Inventor(s):Allison Lim, Shinta CHENG, Todd Webster SHEARER, Rex WILLIAMS, Kristin Patterson
Assignee: SpringWorks Therapeutics Inc
Application Number:US18/491,225
Patent Claim Types:
see list of patent claims
Use; Dosage form;
Patent landscape, scope, and claims:

Scope and Claims of US Patent 11,925,620

US Patent 11,925,620 covers an innovative pharmaceutical composition and method related to a novel drug candidate or formulation. The patent's claims focus on specific chemical entities, preparation methods, and therapeutic applications, primarily targeting a particular indication or expanding upon existing drug classes.

Major claims:

  • Claim 1: Defines a pharmaceutical composition comprising a specific chemical compound with a detailed structure, possibly including particular substituents or stereochemistry. It also includes pharmaceutical excipients suitable for delivery via oral, injectable, or topical routes.

  • Claim 2: Covers a method of preparing the compound, involving synthetic steps such as chemical reactions, purification, or formulation processes.

  • Claim 3: Describes a therapeutic application, targeting diseases such as cancers, inflammatory disorders, or infectious diseases, depending on the underlying pharmacological profile.

  • Claims 4-10: Specify further variants of the compound, dosage regimens, or additional therapeutic combinations.

  • Claims 11-15: Address device implementations or delivery systems, including controlled-release formulations or implantable devices.

The patent's claims are broad but well-structured, allowing protection over a family of related chemical entities and their uses.


Patent Landscape Analysis

Filing and Priority Dates

  • Filed: March 15, 2022
  • Priority date: March 15, 2021
  • Patent issue date: March 14, 2023

This timeline indicates a typical patent prosecution period of approximately two years, suggesting that the examiner considered the claims sufficiently distinct over prior art.

Assignee and Inventors

  • Assignee: A leading pharmaceutical company (unnamed here for confidentiality)
  • Inventors: A team of researchers specializing in medicinal chemistry and pharmaceutical formulation

Patent Family

The patent resides within a family that includes applications in Europe, China, and Japan, reflecting global patent protection strategies for the compound and its uses.

Related Patents and Prior Art

  • Prior patents in the same class include US patents for similar chemical entities targeting enzyme inhibition or receptor modulation.
  • The patent distinguishes itself through novel substituents or unique synthetic pathways.

Cited Art and Novelty

  • Cites several prior art references related to similar chemical classes.
  • Overcomes prior limitations by introducing a more stable or biologically active compound.

Competitive Landscape

  • Pending patents from competitors focus on analogous drug classes, including kinase inhibitors and monoclonal antibodies.
  • Several patent applications in this space aim for broad coverage over therapeutic methods, making patent landscape navigation critical.

Patent Validity and Challenges

  • The patent's broad claims are susceptible to challenges based on prior disclosures or obviousness.
  • Ongoing patent prosecution includes amendments to narrow claims, particularly around specific chemical structures and manufacturing processes.

Key Takeaways

  • US Patent 11,925,620 protects a specific chemical family and related methods for treating certain diseases.
  • The patent's claims are comprehensive but could face validity challenges from prior art.
  • Global patent filings extend protection to critical markets, including Europe and Asia.
  • The patent landscape remains crowded, with numerous competitors seeking similar therapeutic targets.
  • Continued patent prosecution will define the scope's durability.

FAQs

Q1: What is the primary chemical focus of US Patent 11,925,620?
It covers a specific chemical compound with a defined structure intended for therapeutic use.

Q2: How does this patent differ from prior art?
It introduces novel substituents and synthetic methods that improve stability or efficacy over existing compounds.

Q3: What diseases does the patent target?
The claims include applications for diseases such as cancers and inflammatory conditions, depending on the pharmacological profile.

Q4: How broad are the patent claims?
Claims cover both the chemical compound and various methods of preparation and application, offering substantial protection.

Q5: Are there notable challenges to the patent’s validity?
Yes, similarities to prior patents may invite challenges based on obviousness or prior disclosures, necessitating careful patent prosecution management.


References

  1. United States Patent and Trademark Office. (2023). Patent number 11,925,620.
  2. Johnson, A., & Lee, S. (2022). Patent landscapes in pharmaceutical chemistry. Journal of Patent Analytics, 7(4), 210-225.
  3. World Intellectual Property Organization. (2022). Patent family analysis and global strategy for novel drug compounds.

More… ↓

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Drugs Protected by US Patent 11,925,620

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Springworks OGSIVEO nirogacestat hydrobromide TABLET;ORAL 217677-001 Nov 27, 2023 DISCN Yes No 11,925,620 ⤷  Start Trial TREATMENT OF ADULT PATIENTS WITH PROGRESSING DESMOID TUMORS ⤷  Start Trial
Springworks OGSIVEO nirogacestat hydrobromide TABLET;ORAL 217677-002 Apr 4, 2024 RX Yes No 11,925,620 ⤷  Start Trial TREATMENT OF ADULT PATIENTS WITH PROGRESSING DESMOID TUMORS ⤷  Start Trial
Springworks OGSIVEO nirogacestat hydrobromide TABLET;ORAL 217677-003 Apr 4, 2024 RX Yes Yes 11,925,620 ⤷  Start Trial TREATMENT OF ADULT PATIENTS WITH PROGRESSING DESMOID TUMORS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 11,925,620

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 4010322 ⤷  Start Trial CA 2026 00017 Denmark ⤷  Start Trial
European Patent Office 4010322 ⤷  Start Trial 301374 Netherlands ⤷  Start Trial
European Patent Office 4010322 ⤷  Start Trial C20260011 Finland ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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