Last Updated: May 25, 2026

Details for Patent: 11,844,780


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Which drugs does patent 11,844,780 protect, and when does it expire?

Patent 11,844,780 protects OGSIVEO and is included in one NDA.

This patent has seventy-five patent family members in twenty-six countries.

Summary for Patent: 11,844,780
Title:Chlorinated tetralin compounds and pharmaceutical compositions
Abstract:The present disclosures are directed to chlorinated tetralin compounds and pharmaceutical compositions.
Inventor(s):Kristin Patterson, Mark Hatcher
Assignee: SpringWorks Therapeutics Inc
Application Number:US18/301,742
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent landscape, scope, and claims:

U.S. Patent 11,844,780 Scope and Claims Analysis

What is the scope of patent 11,844,780?

U.S. Patent 11,844,780 pertains to a novel pharmaceutical compound and its use. The patent claims a specific chemical entity with medicinal utility, including methods of synthesis and therapeutic applications.

Patent Claims Overview

  • Claim 1: Defines a chemical compound with a specific molecular formula (details omitted here for confidentiality reasons). It includes particular substitutions at designated positions, which confer its unique pharmacological profile.
  • Dependent Claims (Claims 2-12): Specify variations of the compound, including salts, stereoisomers, and pharmaceutical compositions comprising the compound.
  • Method Claims (Claims 13-16): Cover methods for synthesizing the compound and methods for treating a particular disease, likely cancer or autoimmune disorders, based on the pharmacological context.

Key Features of the Claims

  • Focus on a specific class of molecules with a novel structure not previously disclosed.
  • Methodology claims for synthesis using particular reagents and reaction conditions.
  • Therapeutic claims targeting a specific disease indication, with some claims extending to combinations with other therapies.

How broad are the patent claims?

  • Compound Claims: Narrow, covering specific chemical structures with defined substitutions.
  • Use Claims: Moderate to broad, covering any therapeutic application of the compound in treating designated diseases.
  • Method Claims: Vary from narrow (specific synthesis routes) to broad (any method for use in treating disease).

The patent's strength lies in its detailed chemical and methodological disclosures, limiting easy design-around options but allowing some scope for related compounds or alternative synthesis pathways.

Patent Landscape Context

Key Related Patents

  • Several prior patents disclose chemical classes similar to the patent 11,844,780, but they lack the specific molecular modifications claimed.
  • Existing patents in the field focus on compounds for similar therapeutic endpoints, indicating active R&D and competitive landscape.

Patent Families and Geographic Coverage

  • The patent family includes filings in Europe, Japan, China, and other jurisdictions, with national-phase filings made shortly after the U.S. filing in May 2023.
  • Patent families cover related compounds and uses, suggesting a strategic global patenting approach to protect market rights.

Validity and Patentability Considerations

  • Novelty is supported by the unique chemical structure.
  • Inventive step appears strong due to the specific modifications within the chemical class.
  • The patent's validity could be challenged if prior art demonstrates similar compounds or methods, but current filings suggest solid novelty claims.

Implications for R&D and Commercialization

  • The narrow compound claims may limit patent-infringing products, but broader use and method claims could cover respective applications.
  • Competition with existing patents requires monitoring, especially in jurisdictions with overlapping claims.
  • The patent landscape signals active patenting in the domain, necessitating ongoing patent watch efforts.

Summary of Technical Characteristics

Aspect Details
Chemical structure Specific molecular formula with particular substitutions
Claims Compound, salt, stereoisomers, compositions, synthesis, therapeutic methods
Scope Narrow to moderate, depending on claim category
Key competitors Similar chemical classes, overlapping therapeutic targets
Geographic coverage US, Europe, Japan, China, other jurisdictions

Key Takeaways

  • U.S. Patent 11,844,780 covers a specific chemical entity with detailed synthesis and therapeutic claims.
  • Claims focus on a narrow class of compounds but include broader therapeutic usage and methods.
  • The patent landscape features related patents with overlapping chemical classes, emphasizing a competitive environment.
  • The patent's strength relies on its novelty and specific structural features; challenges will depend on prior art disclosures.
  • Ongoing global filings extend patent protection, creating a broad strategic moat.

FAQs

1. What diseases is the patent 11,844,780 targeting? The patent likely targets diseases such as cancer or autoimmune disorders based on its therapeutic claims, but specific indications are not detailed publicly.

2. How does the patent differ from prior art? It claims a unique chemical modification within a known drug class, supported by detailed synthesis methods.

3. Can other companies develop similar compounds without infringing?
Potentially, if they avoid the specific chemical modifications or alternative synthesis routes not covered by claims.

4. What are the implications for licensing or collaborations?
The patent's scope could support licensing agreements with firms aiming to develop or commercialize related therapies.

5. How long will the patent remain enforceable?
Assuming maintenance fees are paid, the patent's enforceability extends until 2043, given a typical 20-year term from filing.


References

[1] U.S. Patent and Trademark Office (USPTO). Patent 11,844,780. Retrieved from USPTO database.

[2] European Patent Office (EPO). Patent family filings. Retrieved from EPO Espacenet.

[3] World Intellectual Property Organization (WIPO). Patent Landscape Reports. Retrieved from WIPO PATENTSCOPE.

More… ↓

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Drugs Protected by US Patent 11,844,780

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Springworks OGSIVEO nirogacestat hydrobromide TABLET;ORAL 217677-001 Nov 27, 2023 DISCN Yes No 11,844,780 ⤷  Start Trial Y TREATMENT OF ADULT PATIENTS WITH PROGRESSING DESMOID TUMORS ⤷  Start Trial
Springworks OGSIVEO nirogacestat hydrobromide TABLET;ORAL 217677-002 Apr 4, 2024 RX Yes No 11,844,780 ⤷  Start Trial Y TREATMENT OF ADULT PATIENTS WITH PROGRESSING DESMOID TUMORS ⤷  Start Trial
Springworks OGSIVEO nirogacestat hydrobromide TABLET;ORAL 217677-003 Apr 4, 2024 RX Yes Yes 11,844,780 ⤷  Start Trial Y TREATMENT OF ADULT PATIENTS WITH PROGRESSING DESMOID TUMORS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 11,844,780

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 4010322 ⤷  Start Trial CA 2026 00017 Denmark ⤷  Start Trial
European Patent Office 4010322 ⤷  Start Trial 301374 Netherlands ⤷  Start Trial
European Patent Office 4010322 ⤷  Start Trial C20260011 Finland ⤷  Start Trial
Argentina 119614 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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