Last Updated: September 24, 2026

Details for Patent: 11,753,419


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Which drugs does patent 11,753,419 protect, and when does it expire?

Patent 11,753,419 protects CAPLYTA and is included in one NDA.

This patent has four patent family members in three countries.

Summary for Patent: 11,753,419
Title:4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′,4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)-1-(4-((6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3′4′:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl)phenyl)butan-1-one for treating conditions of the central nervous system and cardiac disorders
Abstract:The invention relates to a particular substituted heterocycle fused gamma carboline, the compound of Formula I, and new methods and uses pertaining thereto, and pharmaceutical compositions thereof, such as methods of use in the treatment of diseases involving the 5-HT receptor, the serotonin transporter (SERT), and/or pathways involving dopamine D2 receptor signaling, sodium channel activity, and/or norepinephrine transporter activity.
Inventor(s):Peng Li, Robert E DAVIS, Kimberly Vanover
Assignee: Intra Cellular Therapies Inc
Application Number:US17/757,212
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 11,753,419
Patent Claim Types:
see list of patent claims
Use; Composition;

Drugs Protected by US Patent 11,753,419

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Intra-cellular CAPLYTA lumateperone tosylate CAPSULE;ORAL 209500-002 Apr 22, 2022 RX Yes No 11,753,419 ⤷  Start Trial Y Y ⤷  Start Trial
Intra-cellular CAPLYTA lumateperone tosylate CAPSULE;ORAL 209500-003 Apr 22, 2022 RX Yes No 11,753,419 ⤷  Start Trial Y Y ⤷  Start Trial
Intra-cellular CAPLYTA lumateperone tosylate CAPSULE;ORAL 209500-001 Dec 20, 2019 RX Yes Yes 11,753,419 ⤷  Start Trial Y Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

International Family Members for US Patent 11,753,419

Country Patent Number Estimated Expiration Supplementary Protection Certificate SPC Country SPC Expiration
European Patent Office 4072554 ⤷  Start Trial
Japan 2022550635 ⤷  Start Trial
Japan 7261942 ⤷  Start Trial
World Intellectual Property Organization (WIPO) 2021119334 ⤷  Start Trial
>Country >Patent Number >Estimated Expiration >Supplementary Protection Certificate >SPC Country >SPC Expiration

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