Last Updated: August 9, 2026

Details for Patent: 10,695,339


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Which drugs does patent 10,695,339 protect, and when does it expire?

Patent 10,695,339 protects COBENFY and is included in one NDA.

This patent has nineteen patent family members in nine countries.

Summary for Patent: 10,695,339
Title:Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
Abstract:The present disclosure provides a method of treating a central nervous system disorder in a patient in need thereof. The method comprises orally administering between 75 mg and 300 mg xanomeline salt and between 20 mg and 200 mg trospium chloride to the patient during a 24-hour period, the central nervous system disorder being selected from schizophrenia, Alzheimer's disease, Huntington's disease, Parkinson's disease, and Lewy Body dementia, wherein use of the trospium chloride alleviates a side effect associated with use of the xanomeline salt.
Inventor(s):Eric Elenko, Philip E. Murray, III, Andrew C. Miller
Assignee: Puretech Health LLC , Puretech Management Inc
Application Number:US16/444,206
Patent Claim Types:
see list of patent claims
Use;

Drugs Protected by US Patent 10,695,339

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Bristol-myers COBENFY trospium chloride; xanomeline tartrate CAPSULE;ORAL 216158-001 Sep 26, 2024 RX Yes Yes ⤷  Start Trial ⤷  Start Trial TREATMENT OF SCHIZOPHRENIA IN ADULTS ⤷  Start Trial
Bristol-myers COBENFY trospium chloride; xanomeline tartrate CAPSULE;ORAL 216158-002 Sep 26, 2024 RX Yes No ⤷  Start Trial ⤷  Start Trial TREATMENT OF SCHIZOPHRENIA IN ADULTS ⤷  Start Trial
Bristol-myers COBENFY trospium chloride; xanomeline tartrate CAPSULE;ORAL 216158-003 Sep 26, 2024 RX Yes No ⤷  Start Trial ⤷  Start Trial TREATMENT OF SCHIZOPHRENIA IN ADULTS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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