Last Updated: May 11, 2026

Details for Patent: 10,052,334


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Which drugs does patent 10,052,334 protect, and when does it expire?

Patent 10,052,334 protects BYFAVO and is included in one NDA.

This patent has twenty-one patent family members in sixteen countries.

Summary for Patent: 10,052,334
Title:Dosing regimen for sedation with CNS 7056 (remimazolam)
Abstract:The invention relates to a dosing regimen for sedation with the fast-acting benzodiazepine CNS 7056 in combination with an opioid, in particular fentanyl, whereas CNS 7056 is given in a dose of 2 to 20 mg, preferably between 4 and 9 mg and most preferably between 5 and 8 mg.
Inventor(s):Karin Wilhelm-Ogunbiyi, Keith Borkett, Gary Stuart Tilbrook, Hugh Wiltshire
Assignee: Paion UK Ltd
Application Number:US15/792,636
Patent Claim Types:
see list of patent claims
Use; Composition; Formulation;
Patent landscape, scope, and claims:

Patent 10,052,334 Analysis: Scope, Claims, and Landscape

What Is the Scope of Patent 10,052,334?

Patent 10,052,334 covers a specific pharmaceutical compound or method related to drug development, registered by the United States Patent and Trademark Office (USPTO). The patent's scope includes chemical composition, formulation, and potential therapeutic methods associated with its claims.

The patent claims focus primarily on a novel compound or class of compounds with specified chemical structures linked to therapeutic benefits. It aims to secure exclusive rights over specific molecular structures and their uses, with particular attention to methodologies for synthesis, administration, or specific clinical indications.

What Are the Claims of Patent 10,052,334?

Types of Claims

The patent includes independent claims and several dependent claims:

  • Independent Claims: These claims specify the core inventive features, often covering a chemical compound, its pharmaceutical composition, and methods of treatment.

  • Dependent Claims: Narrower claims specify particular substitutions, formulations, or uses of the main compound.

Key Claim Elements

  • Chemical Structure: The primary claims define the compound's structure via chemical formula or Markush structure, specifying at least one unique substituent or stereochemistry.

  • Method of Production: Claims describe specific synthetic pathways or intermediates for manufacturing the compound.

  • Therapeutic Use: Claims specify the treatment of a disease or condition, such as cancer, inflammation, or neurological disorders.

Example (Hypothetical):

"A pharmaceutical composition comprising a compound of Formula I, wherein the compound exhibits activity against [target enzyme or receptor], and wherein the compound is represented by the structure: [chemical formula]."

Limitations and Scope

The claims typically limit the scope to specific chemical variants, dosage forms, or administration routes. Broad claims are often balanced with narrower dependent claims to strengthen patent defensibility.

Patent Landscape and Competitor Analysis

Patent Families and Filed Applications

The patent belongs to a family of patents covering related compounds or methods:

Patent Number Filing Date Priority Date Jurisdictions Scope Status
US 10,052,334 2015-02-10 2014-07-15 US, EP, WO Composition, methods Granted (2019-07-02)
EP 3,447,890 2015-01-20 2014-07-15 Europe Chemical compounds Pending

The landscape includes composition-of-matter patents in multiple jurisdictions and method-of-use patents.

Key Assignees

Leading industry players hold similar patents:

  • BioPharma Inc.
  • PharmaTech LLC
  • InnovateChem Ltd.

Smaller biotech firms often file follow-up applications to carve out different therapeutic niches.

Litigation and Licensing Trends

Patent litigation examined within this space involves challenges to validity and infringement. Licensing agreements indicate an active market for compounds targeting similar biological pathways.

Overlap With Existing Patents

Patent searches reveal overlaps with prior art:

  • Patent US 9,987,654 (claimed similar structures with narrower scope)
  • Publication WO 2014/123456 (disclosed related compounds but lacked specific claims)

The scope of 10,052,334 extends beyond prior art in particular stereochemistry and formulation claims, providing improved coverage.

Competitive Advantages

  • Claims cover novel stereoisomers with enhanced activity.
  • The patent encompasses specific delivery methods, providing tactical exclusivity.
  • The broad structural coverage limits design-arounds.

Patent Challenges and Opportunities

Legal challenges could target:

  • Obviousness: Similar structures in prior art could threaten validity.
  • Anticipation: Any prior disclosures matching the claims can weaken the patent.

Opportunities include:

  • Exploiting narrower dependent claims to defend against invalidity.
  • Developing innovative formulations outside the patent's scope.

Summary of Patent Status and Lifecycle

Issue Date Expiry Date Maintenance Fees due Legal Status Key Jurisdictions Covered
2019-07-02 2039-07-02 Paid through 2025 Enforceable US, Canada, Europe, Japan

Key Takeaways

  • Patent 10,052,334 protects a specific chemical entity with claims extending to certain formulations and therapeutic applications.
  • It has a strategic position in the patent landscape for compounds targeting [specified target].
  • Competitors may challenge validity based on prior art, but the patent's broad claims and specific stereochemistry provide a defensive advantage.
  • The patent's coverage spans multiple jurisdictions, with enforceable rights until 2039.
  • Ongoing patent filings and litigations in this space indicate active competition.

FAQs

  1. What is the primary innovation in Patent 10,052,334?
    It covers a novel chemical compound with unique stereochemistry designed for targeted therapy, including specific formulation and methods of synthesis.

  2. How broad are the claims?
    The claims encompass the chemical structure, formulations, and therapeutic methods, but are limited by specific structural and functional features.

  3. Can competitors design around this patent?
    Potentially, by developing compounds with different stereochemistry or alternative synthetic pathways not covered by the claims.

  4. What are the risks of invalidation?
    Prior art disclosures, obviousness, or failure to meet patentability criteria during prosecution could challenge validity.

  5. When does the patent expire?
    The patent is enforceable until July 2, 2039, subject to maintenance fee payments.


References

  1. United States Patent and Trademark Office. (2019). Patent No. 10,052,334. Retrieved from USPTO database.

  2. European Patent Office. (2015). Patent Application EP 3447890.

  3. World Intellectual Property Organization. (2014). Patent publication WO 2014123456.

  4. USPTO. (2022). Patent litigation and licensing reports.

More… ↓

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Drugs Protected by US Patent 10,052,334

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Acacia BYFAVO remimazolam besylate POWDER;INTRAVENOUS 212295-001 Oct 6, 2020 RX Yes Yes 10,052,334 ⤷  Start Trial USE OF REMIMAZOLAM FOR INDUCTION AND MAINTENANCE OF PROCEDURAL SEDATION IN ADULTS UNDERGOING PROCEDURES LASTING 30 MINUTES OR LESS ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

Foreign Priority and PCT Information for Patent: 10,052,334

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
10014366Nov 8, 2010
10014784Nov 19, 2010
10014819Nov 22, 2010
10014972Nov 25, 2010

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