Last Updated: November 8, 2026

Details for Patent: 10,047,053

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Which drugs does patent 10,047,053 protect, and when does it expire?

Patent 10,047,053 protects ALYFTREK and is included in one NDA.

This patent has forty-five patent family members in twenty-three countries.

Summary for Patent: 10,047,053
Title:Deuterated CFTR potentiators
Abstract:This invention relates to compounds of Formula I: and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a CFTR potentiator.
Inventor(s):Adam J. Morgan
Assignee: Vertex Pharmaceuticals Europe Ltd
Application Number:US15/827,792
Patent Litigation and PTAB cases: See patent lawsuits and PTAB cases for patent 10,047,053
Patent Claim Types:
see list of patent claims
Use; Compound;

Drugs Protected by US Patent 10,047,053

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use Submissiondate
Vertex Pharms Inc ALYFTREK deutivacaftor; tezacaftor; vanzacaftor calcium TABLET;ORAL 218730-001 Dec 20, 2024 RX Yes No 10,047,053 ⤷  Start Trial Y ⤷  Start Trial
Vertex Pharms Inc ALYFTREK deutivacaftor; tezacaftor; vanzacaftor calcium TABLET;ORAL 218730-002 Dec 20, 2024 RX Yes Yes 10,047,053 ⤷  Start Trial Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Patented / Exclusive Use >Submissiondate

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