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Last Updated: June 18, 2025

Drugs in MeSH Category Astringents


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Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Zydus Pharms ZINC SULFATE zinc sulfate SOLUTION;INTRAVENOUS 217074-002 Aug 22, 2023 AP RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Aspiro ZINC SULFATE zinc sulfate SOLUTION;INTRAVENOUS 219585-001 May 1, 2025 AP RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Am Regent ZINC SULFATE zinc sulfate SOLUTION;INTRAVENOUS 209377-002 Jul 18, 2019 AP RX Yes Yes ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Abraxis Pharm ZINC SULFATE zinc sulfate INJECTABLE;INJECTION 019229-002 May 5, 1987 DISCN No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Nivagen Pharms Inc ZINC SULFATE zinc sulfate SOLUTION;INTRAVENOUS 214597-002 Jul 5, 2024 AP RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Nivagen Pharms Inc ZINC SULFATE zinc sulfate SOLUTION;INTRAVENOUS 214597-001 Jul 5, 2024 AP RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
Apotex ZINC SULFATE zinc sulfate SOLUTION;INTRAVENOUS 218059-001 Jun 10, 2024 AP RX No No ⤷  Try for Free ⤷  Try for Free ⤷  Try for Free
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Astringents Market Analysis and Financial Projection

The astringent drug market and its patent landscape are evolving dynamically, driven by advancements in formulation technologies, expanding therapeutic applications, and shifting consumer preferences towards natural ingredients. Here's a detailed analysis:


Market Dynamics

Growth Projections and Segments

  • The global astringent market is projected to grow at a CAGR of 8.4% (2025–2031), with demand fueled by rising adoption in skincare, surgical procedures, and industrial applications like water treatment and leather tanning[1][14].
  • Segments by product type:
    • Chemical astringents (e.g., aluminum acetate) dominate medical use for wound care[6].
    • Natural/herbal astringents (witch hazel, tea tree oil) are gaining traction in cosmetics due to eco-friendly trends[17].
  • Key end-users: Hospitals, surgical centers, and cosmetics/pharmaceutical industries[1][6].

Drivers and Opportunities

  • Skincare demand: Rising consumer focus on acne treatment and oily skin management[6][17].
  • Technological innovations:
    • Natural ingredient integration (e.g., seaweed-based formulations for hydration + pore-tightening)[1].
    • AI-driven personalization for tailored skincare solutions[1].
  • Sustainability: Ethically sourced raw materials and eco-friendly production methods[1].

Challenges

  • Irritation risks: High alcohol content in traditional formulations[7].
  • Regulatory scrutiny: Ensuring safety and efficacy in medical-grade products[6].

Patent Landscape

Key Trends

  • Cosmetic formulations:
    • L’Oréal’s US8974804: Oil-in-water emulsion with elastomeric silicones for stabilized delivery[2].
    • Avon’s US8815265: Anti-aging sulfonyloxybenzylamines targeting biochemical pathways[2].
  • Therapeutic diversification:
    • Anti-inflammatory patents: Polyphenols (e.g., strictinin) for allergy and eczema treatments[2].
    • Hydrogel composites: Laponite-based systems to reduce burst drug release[5].

Innovation Focus

  • Delivery systems: Patents emphasize controlled-release mechanisms (e.g., gel matrices, emulsions) to enhance efficacy[2][5].
  • Natural actives: Plant-derived compounds (witch hazel, green tea) replace synthetic agents[2][6].

Classification and Search

  • MeSH integration: Astringents are classified under D001252 (Agents causing tissue contraction)[16].
  • Challenges in patent retrieval: Structural differences between MeSH and International Patent Classification (IPC) hinder cross-referencing[13].

Competitive Landscape

  • Major players: L’Oréal, Avon, Beiersdorf, and Achieve Life Sciences (novel salt formulations like cytisinicline succinate)[2][4].
  • Strategic moves: Mergers, sustainability initiatives, and R&D investments in natural/organic products[1][14].

Future Outlook

  • Personalized medicine: AI-driven formulations for specific skin types[1].
  • Expansion into emerging markets: Asia-Pacific’s growing middle class and healthcare infrastructure[6][17].

Highlight: “Natural and organic astringents are transforming skincare, merging efficacy with sustainability”—The Insight Partners[1].


This market’s growth hinges on balancing innovation with safety, while patents reflect a shift toward multifunctional, eco-conscious solutions. Integration of MeSH classifications in patent databases could further streamline research and development[10][11].

References

  1. https://www.theinsightpartners.com/reports/astringent-professional-market
  2. https://patents.justia.com/patents-by-us-classification/514/848
  3. https://www.uv.es/fhersan/EVES2013/NLM%20Classification/nlmclass/class_qv.html
  4. https://www.biospace.com/achieve-announces-patent-granted-in-the-u-s-for-novel-formulation-of-cytisinicline
  5. https://mdpi-res.com/bookfiles/book/8707/Feature_Reviews_in_Pharmaceutical_Technology.pdf?v=1741831696
  6. https://sites.google.com/view/focused-insights/us-astringent-market-by-type
  7. https://patents.google.com/patent/US6482446B2/en
  8. https://www.cda-amc.ca/sites/default/files/cdr/clinical/SR0452_Pheburane_CL_Report.pdf
  9. https://www.youtube.com/watch?v=o6CTfdx85ys
  10. https://pubmed.ncbi.nlm.nih.gov/20865561/
  11. https://ceur-ws.org/Vol-2032/om2017_Tpaper4.pdf
  12. https://www.nlm.nih.gov/pubs/techbull/nd24/nd24_annual_mesh_processing.html
  13. https://pubmed.ncbi.nlm.nih.gov/23734562/
  14. https://www.marketresearchfuture.com/reports/astringent-professional-market-40090
  15. https://pubmed.ncbi.nlm.nih.gov/10857475/
  16. https://meshb.nlm.nih.gov/record/ui?ui=D001252
  17. https://github.com/marlanamarvn/Market-Research-Report-List-1/blob/main/astringent-market.md
Last updated: 2025-03-24

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