➤ Get the DrugPatentWatch Daily Briefing

Get Daily Updates on Generic Entry, Litigation, Biosimilars, and more …

Serving leading biopharmaceutical companies globally:

Johnson and Johnson
McKesson
Mallinckrodt
AstraZeneca
Moodys
Medtronic

Last Updated: May 31, 2020

DrugPatentWatch Database Preview

Saquinavir mesylate - Generic Drug Details

» See Plans and Pricing

« Back to Dashboard

What are the generic drug sources for saquinavir mesylate and what is the scope of freedom to operate?

Saquinavir mesylate is the generic ingredient in one branded drug marketed by Hoffmann La Roche and Hoffmann-la Roche, and is included in two NDAs. Additional information is available in the individual branded drug profile pages.

There is one drug master file entry for saquinavir mesylate. One supplier is listed for this compound.

Recent Clinical Trials for saquinavir mesylate

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
AIDS Clinical Trials GroupN/A
National Institute of Allergy and Infectious Diseases (NIAID)N/A
AbbottPhase 2

See all saquinavir mesylate clinical trials

Pharmacology for saquinavir mesylate
Synonyms for saquinavir mesylate
(2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1-phenylbutan-2-yl]-2-(quinoline-2-carbonylamino)butanediamide;methanesulfonic acid
(2S)-N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide methanesulfonate
(2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide methanesulfonate
(S)-N-((alphaS)-alpha-((1R)-2-((3S,4aS,8aS)-3-(tert-Butylcarbamoyl)octahydro-2(1H)-isoquinolyl)-1-hydroxyethyl)phenethyl)-2-quinaldamidosuccinamide monomethanesulfonate (salt)
(S)-N1-((2S,3R)-4-((3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl)-3-hydroxy-1-phenylbutan-2-yl)-2-(quinoline-2-carboxamido)succinamide methanesulfonate
127779-20-8 (base)
149845-06-7
845S067
AC-1333
AKOS015962362
AOB1668
Butanediamide, N(sup 1)-(3-(3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (3S-(2(1R*(R*),2S*),3alpha,4abeta,8abeta))-, monomethanesul
Butanediamide, N1-((1S,2R)-3-((3S,4aS,8aS)-3-(((1,1-dimethylethyl)amino)carbonyl)octahydro-2(1H)-isoquinolinyl)-2-hydroxy-1-(phenylmethyl)propyl)-2-((2-quinolinylcarbonyl)amino)-, (2S)-, monomethanesulfonate (salt)
Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, methanesulfonate (1:1)
C12560
C38H50N6O5
CAS-149845-06-7
CCG-100992
CHEBI:32121
CHEMBL282042
CPD000469290
CTK8E9063
D01160
DSSTox_CID_3835
DSSTox_GSID_23835
DSSTox_RID_77202
DTXSID9023835
Fortovase
HMS1571O10
HMS2051D04
HMS2098O10
HMS2231C15
HMS3715O10
Invirase
Invirase (TN)
IRHXGOXEBNJUSN-YOXDLBRISA-N
J-008634
KS-1110
LS-872
MFCD00944907
MLS001401395
N-t-butyl-decahydro-2-[2(R)-hydroxy-4-phenyl-3(S)-[[N-(2-quinolylcarbonyl)-L-asparaginyl]amino]butyl]-(4aS,8aS)-isoquinoline-3(S)-carboxamide methanesulphonate
N1-{(1S,2R)-1-benzyl-3-[(3S,4aS,8aS)-3-[(tert-butylamino)carbonyl]octahydroisoquinolin-2(1H)-yl]-2-hydroxypropyl}-N2-(quinolin-2-ylcarbonyl)-L-aspartamide methanesulfonate (salt)
NC00242
NCGC00091469-01
NCGC00260082-01
Q27114794
R-56
Ro 31-8959
Ro 31-8959/003
Ro-31-8959-003
Ro-31-8959/003
Ro-318959003
RT-015634
SAM001246578
Saquinavir for system suitability, European Pharmacopoeia (EP) Reference Standard
Saquinavir mesilate
Saquinavir mesilate (JAN)
Saquinavir mesilate, European Pharmacopoeia (EP) Reference Standard
Saquinavir mesylate (AIDS Initiative)
Saquinavir mesylate (USP)
Saquinavir mesylate [USAN:USP]
Saquinavir mesylate [USAN]
Saquinavir mesylate, >=98% (HPLC), powder
Saquinavir mesylate, 98%
Saquinavir mesylate, United States Pharmacopeia (USP) Reference Standard
Saquinavir methanesulfonate salt
Saquinavir Monomethanesulfonate
Saquinavir monomethanesulfonate salt
Saquinavir, Mesylate
SCHEMBL42352
SMR000469290
SQV
SR-01000763454
SR-01000763454-4
Tox21_111137
Tox21_202533
UHB9Z3841A
UNII-UHB9Z3841A
W-5240

US Patents and Regulatory Information for saquinavir mesylate

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Hoffmann-la Roche INVIRASE saquinavir mesylate TABLET;ORAL 021785-001 Dec 17, 2004 RX Yes Yes   Start Trial   Start Trial   Start Trial
Hoffmann La Roche INVIRASE saquinavir mesylate CAPSULE;ORAL 020628-001 Dec 6, 1995 DISCN Yes No   Start Trial   Start Trial   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Expired US Patents for saquinavir mesylate

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Hoffmann La Roche INVIRASE saquinavir mesylate CAPSULE;ORAL 020628-001 Dec 6, 1995   Start Trial   Start Trial
Hoffmann-la Roche INVIRASE saquinavir mesylate TABLET;ORAL 021785-001 Dec 17, 2004   Start Trial   Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >Patent No. >Patent Expiration

Make Better Decisions: Try a trial or see plans & pricing

Serving leading biopharmaceutical companies globally:

Johnson and Johnson
McKesson
Mallinckrodt
AstraZeneca
Moodys
Medtronic

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.