Get our Free Patent Expiration Newsletter

Serving hundreds of leading biopharmaceutical companies globally:

Cantor Fitzgerald
US Department of Justice
AstraZeneca
Federal Trade Commission
Moodys
UBS

Generated: September 22, 2019

DrugPatentWatch Database Preview

Melphalan hydrochloride - Generic Drug Details

  Try a free trial


See Plans and Pricing

« Back to Dashboard

What are the generic sources for melphalan hydrochloride and what is the scope of melphalan hydrochloride freedom to operate?

Melphalan hydrochloride is the generic ingredient in three branded drugs marketed by Apotex Inc, Actavis Llc, Alvogen Inc, Dr Reddys Labs Ltd, Fresenius Kabi Usa, Gland Pharma Ltd, Mylan Institutional, Par Sterile Products, Sagent Pharms, Us Worldmeds Llc, West-ward Pharms Int, and Acrotech, and is included in thirteen NDAs. There are four patents protecting this compound and one Paragraph IV challenge. Additional information is available in the individual branded drug profile pages.

Melphalan hydrochloride has sixty-nine patent family members in seventeen countries.

There are twelve drug master file entries for melphalan hydrochloride. Twelve suppliers are listed for this compound.

Pharmacology for melphalan hydrochloride
Drug ClassAlkylating Drug
Mechanism of ActionAlkylating Activity
Synonyms for melphalan hydrochloride
(2S)-2-amino-3-[4-[bis(2-chloroethyl)amino]phenyl]propanoic acid;hydrochloride
(S)-2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanoic acid hydrochloride
1VXP4V453T
223M072
3223-07-2
4-[Bis(2-chloroethyl)-amino]-L-phenylalanine hydrochloride
4-[bis(2-chloroethyl)-amino]-phenylalanine hydrochloride
AC-25549
AI3-26377
AKOS025401785
Alanine nitrogen mustard hydrochloride
ALANINE, 3-(p-(BIS(2-CHLOROETHYL)AMINO)PHENYL)-, MONOHYDROCHLORIDE, L-
Alkeran (GlaxoSmith)
ALKERAN (TN)
Alkeran hydrochloride
BC208857
CB 3025 hydrochloride
CHEMBL1200863
CTK8G0783
D08173
DTXSID60872785
Evomela (TN)
FT-0773182
L-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine monohydrochloride
L-Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, hydrochloride
L-Alanine, hydrochloride
L-Phenylalanine mustard hydrochloride
L-Phenylalanine, 4-(bis(2-chloroethyl)amino)-, monohydrochloride (9CI)
L-Phenylalanine, monohydrochloride
L-Sarcolysine hydrochloride
Melfalan hydrochloride
Melphalan HCl
NSC8806
OUUYBRCCFUEMLH-YDALLXLXSA-N
Phenylalanine mustard hydrochloride
SCHEMBL41335
SK 15673
UNII-1VXP4V453T
UNII-GEG3Q4FC64 component OUUYBRCCFUEMLH-YDALLXLXSA-N
WLN: QVYZ1R DN2G2G &GH

US Patents and Regulatory Information for melphalan hydrochloride

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Gland Pharma Ltd MELPHALAN HYDROCHLORIDE melphalan hydrochloride INJECTABLE;INJECTION 209826-001 May 28, 2019 AP RX No No   Try a Free Trial   Try a Free Trial   Try a Free Trial
Acrotech EVOMELA melphalan hydrochloride POWDER;INTRAVENOUS 207155-001 Mar 10, 2016 RX Yes Yes   Try a Free Trial   Try a Free Trial Y   Try a Free Trial
Apotex Inc ALKERAN melphalan hydrochloride INJECTABLE;INJECTION 020207-001 Nov 18, 1992 AP RX Yes No   Try a Free Trial   Try a Free Trial   Try a Free Trial
Acrotech EVOMELA melphalan hydrochloride POWDER;INTRAVENOUS 207155-001 Mar 10, 2016 RX Yes Yes   Try a Free Trial   Try a Free Trial Y   Try a Free Trial
Mylan Institutional MELPHALAN HYDROCHLORIDE melphalan hydrochloride INJECTABLE;INJECTION 090270-001 Jun 9, 2009 AP RX No Yes   Try a Free Trial   Try a Free Trial   Try a Free Trial
Us Worldmeds Llc MELPHALAN HYDROCHLORIDE melphalan hydrochloride INJECTABLE;INJECTION 207032-001 May 3, 2019 AP RX No No   Try a Free Trial   Try a Free Trial   Try a Free Trial
Alvogen Inc MELPHALAN HYDROCHLORIDE melphalan hydrochloride INJECTABLE;INJECTION 204817-001 May 17, 2019 AP RX No No   Try a Free Trial   Try a Free Trial   Try a Free Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

International Patents for melphalan hydrochloride

Make Better Decisions: Try a trial or see plans & pricing

Serving hundreds of leading biopharmaceutical companies globally:

Healthtrust
AstraZeneca
UBS
Harvard Business School
Deloitte
Fuji

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.