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Generated: September 23, 2018

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Esmolol hydrochloride - Generic Drug Details

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What are the generic sources for esmolol hydrochloride and what is the scope of esmolol hydrochloride patent protection?

Esmolol hydrochloride is the generic ingredient in six branded drugs marketed by Baxter Hlthcare, Aurobindo Pharma Ltd, Fresenius Kabi Usa, Luitpold, Mylan Institutional, Mylan Labs Ltd, Sagent Pharms, West-ward Pharms Int, and Hq Spclt Pharma, and is included in nine NDAs. There are six patents protecting this compound and one Paragraph IV challenge. Additional information is available in the individual branded drug profile pages.

There are eight drug master file entries for esmolol hydrochloride. Twelve suppliers are listed for this compound.

Pharmacology for esmolol hydrochloride
Synonyms for esmolol hydrochloride
(+-)-Methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate hydrochloride
(+/-)-methyl p-[2-hydroxy-3-(isopropylamino) propoxy]hydrocinnamate hydrochloride
4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoic acid methyl ester HCl
4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benxzenepropanoic Acid Methyl Ester Hydrochloride
4-[2-HYDROXY-3-[(1-METHYLETHYL)AMINO]PROPOXY]BENZENEPROPANOIC ACID METHYL ESTER HYDROCHLORIDE
4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester hydrochloride hydrochloride
598E034
81147-92-4 (Parent)
81161-17-3
81161-17-3, 81147-92-4(free base)
AB0013228
AB07716
AC-6972
AC1L2XGQ
AC1Q3EA6
AKOS015895316
AN-9460
API0001758
Asl 8052
ASL-8052
Benzenepropanoic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, methyl ester, hydrochloride
Benzenepropanoic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, methyl ester, hydrochloride, (+-)-
Benzenepropanoic acid, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, methyl ester,hydrochloride
BG0502
Brevibloc
Brevibloc (TN)
Brevibloc Double Strength in plastic container
Brevibloc in plastic container
C16H25NO4.HCl
CAS-81161-17-3
CCG-100972
CCG-220890
CHEBI:4857
CHEMBL1201115
CPD000469141
CS-4908
CTK8F9497
D00644
DSSTox_CID_28929
DSSTox_GSID_49003
DSSTox_RID_83195
DTXSID7049003
EBD13377
Esmolol (hydrochloride)
Esmolol HCL
Esmolol hydrochloride (JAN/USAN)
Esmolol hydrochloride [USAN]
Esmolol hydrochloride, >=98% (HPLC), solid
Esmolol hydrochloride, United States Pharmacopeia (USP) Reference Standard
Esmolol(hydrochloride)
Esmololhydrochloride
FT-0082446
FT-0601541
H746
HSDB 6530
HY-B1392
I06-0682
J-003862
KS-00001FBX
KS-1353
LS-31122
methyl 3-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)propanoate hydrochloride
METHYL 3-(4-[2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY]PHENYL)PROPANOATE HYDROCHLORIDE
methyl 3-(4-{2-hydroxy-3-[(methylethyl)amino]propoxy}phenyl)propanoate, chlori de
METHYL 3-[4-(2-HYDROXY-3-PROPAN-2-YLAMINO-PROPOXY)PHENYL]PROPANOATE HYDROCHLORIDE
Methyl 3-[4-(2-hydroxy-3-propan-2-ylamino-propoxy)phenyl]propanoate hydrochloride; Brevibloc
methyl 3-[4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]propanoate hydrochloride
methyl 3-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]propanoate hydrochloride
Methyl 3-{4-[2-Hydroxy-3-(isopropylamino)propoxy]phenyl}propanoate hydrochloride (Esmolol HCl)
MLS001401393
MolPort-003-847-093
NC00222
NCGC00185766-01
NCGC00185766-04
OR161498
Q-201070
s4100
SAM001246533
SBB055181
SCHEMBL41086
SMR000469141
TL8005428
Tox21_113496
Tox21_113496_1
W-1240

US Patents and Regulatory Information for esmolol hydrochloride

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Hq Spclt Pharma ESMOLOL HYDROCHLORIDE DOUBLE STRENGTH IN PLASTIC CONTAINER esmolol hydrochloride SOLUTION;INTRAVENOUS 205703-002 Apr 7, 2016 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Hq Spclt Pharma ESMOLOL HYDROCHLORIDE DOUBLE STRENGTH IN PLASTIC CONTAINER esmolol hydrochloride SOLUTION;INTRAVENOUS 205703-002 Apr 7, 2016 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Baxter Hlthcare BREVIBLOC esmolol hydrochloride INJECTABLE;INJECTION 019386-006 Feb 25, 2003 AP RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Expired US Patents for esmolol hydrochloride

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Baxter Hlthcare BREVIBLOC esmolol hydrochloride INJECTABLE;INJECTION 019386-003 Aug 15, 1988 ➤ Sign Up ➤ Sign Up
Baxter Hlthcare BREVIBLOC esmolol hydrochloride INJECTABLE;INJECTION 019386-006 Feb 25, 2003 ➤ Sign Up ➤ Sign Up
Baxter Hlthcare BREVIBLOC esmolol hydrochloride INJECTABLE;INJECTION 019386-003 Aug 15, 1988 ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Farmers Insurance
Express Scripts
QuintilesIMS
Mallinckrodt
Medtronic
Chinese Patent Office
Teva
Fish and Richardson
Argus Health

Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. thinkBiotech performs no independent verifification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.