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Generated: December 10, 2018

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RAUWOLFIA SERPENTINA ROOT - Generic Drug Details

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What are the generic drug sources for rauwolfia serpentina root and what is the scope of rauwolfia serpentina root patent protection?

Rauwolfia serpentina root is the generic ingredient in eight branded drugs marketed by Bowman Pharms, Phys Prods Va, Panray, Apothecon, Ferndale Labs, Pal Pak, Bundy, Halsey, Impax Labs, Ivax Sub Teva Pharms, Purepac Pharm, Pvt Form, Solvay, Tablicaps, Valeant Pharm Intl, Watson Labs, and Forest Pharms, and is included in nineteen NDAs. Additional information is available in the individual branded drug profile pages.

There are eight drug master file entries for rauwolfia serpentina root.

Summary for RAUWOLFIA SERPENTINA ROOT
Synonyms for RAUWOLFIA SERPENTINA ROOT
(7aR,8S,11aS,12aS)-8-Methyl-5,6,7a,8,11a,12,12a,13-octahydro-7H-9-oxa-6a,13-diaza-indeno[2,1-a]anthracene-11-carboxylic acid methyl ester
16,17-Didehydro-19-methyloxayohimban-16-carboxylic acid methyl ester
19-Epiajmalicine
19b-methyl-16-methoxycarbonyl-16,17-didehydro-oxayohimbane
4-27-00-07927 (Beilstein Handbook Reference)
483-04-5
483A045
4QJL8OX71Z
AC-20175
AC1L9C1B
ACon1_001630
Ajmalicin
Ajmalicine
Ajmalicine(-Yohimbine)
AJN
AKOS015895125
Alkaloid C
Alkaloid F
Alkaloid II
API0004044
BDBM50030612
Bio-0252
BPBio1_000512
BRD-K83028735-001-01-6
BRD-K83028735-003-03-8
BRN 0097268
BSPBio_000464
BT000576
C09024
C21H24N2O3
CAS-4373-34-6
CAS-6474-90-4
CHEBI:2524
CHEMBL123325
Circolene
D08470
D0U7GP
delta-Yohimbine
DivK1c_006521
DR001793
EINECS 207-589-5
GRTOGORTSDXSFK-XJTZBENFSA-N
GTPL8746
Hydrosarpan
KBio1_001465
KBio2_001255
KBio2_003823
KBio2_006391
KBioSS_001255
Lamuran
Lamuran (TN)
LS-15651
LS-187727
MEGxp0_001818
Methyl (19-methyl-16,17-dehydro-18-oxa-3alpha,15alpha,19beta,20beta-yohimban-16-carboxylat)
Methyl (19alpha)-19-methyl-16,17-didehydro-18-oxayohimban-16-carboxylate
methyl (19alpha)-19-methyl-16,17-didehydrooxayohimban-16-carboxylate
METHYL (1S,15R,16S,20S)-16-METHYL-17-OXA-3,13-DIAZAPENTACYCLO[11.8.0.0(2),(1)?.0?,?.0(1)?,(2)?]HENICOSA-2(10),4,6,8,18-PENTAENE-19-CARBOXYLATE
Methyl 16,17-didehydro-19alpha-methyl-18-oxayohimban-16-carboxylat
MFCD00042748
NCGC00016647-01
NCGC00016647-02
NCGC00016647-03
NCGC00016647-04
NSC 72133
Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19-.alpha).-
Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19-alpha)-
Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19-alpha)- (9CI)
Oxayohimban-16-carboxylicacid, 16,17-didehydro-19-methyl-, methyl ester, (19a)-
PL057365
Prestwick0_000592
Prestwick1_000592
Prestwick2_000592
Prestwick3_000592
py-Tetrahydroserpentine
Ranitol
Raubaserp
Raubasil
Raubasin
Raubasine
Raubasine (DCF)
Raumalina
Rauvasan
rauwolfia alkaloid
Sarpan
SC-80963
SCHEMBL309914
SPBio_002683
SpecPlus_000425
Spectrum_000775
Substance II
Tensyl
Tetrahydroalstonine
Tetrahydroserpentine
UNII-4QJL8OX71Z
Vincain
Vincein
Vinceine
W-106052
ZINC53147422

US Patents and Regulatory Information for RAUWOLFIA SERPENTINA ROOT

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Halsey RAUWOLFIA SERPENTINA rauwolfia serpentina root TABLET;ORAL 080498-001 Approved Prior to Jan 1, 1982 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Purepac Pharm RAUWOLFIA SERPENTINA rauwolfia serpentina root TABLET;ORAL 080842-001 Approved Prior to Jan 1, 1982 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Apothecon RAUDIXIN rauwolfia serpentina root TABLET;ORAL 008842-002 Approved Prior to Jan 1, 1982 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Watson Labs RAUWOLFIA SERPENTINA rauwolfia serpentina root TABLET;ORAL 080907-001 Approved Prior to Jan 1, 1982 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Forest Pharms WOLFINA rauwolfia serpentina root TABLET;ORAL 009255-006 Approved Prior to Jan 1, 1982 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Accenture
Mallinckrodt
Citi
Daiichi Sankyo
QuintilesIMS
Harvard Business School
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Queensland Health
Colorcon

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