BOTOX COSMETIC Drug Profile
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Summary for Tradename: BOTOX COSMETIC
| High Confidence Patents: | 11 |
| Applicants: | 1 |
| BLAs: | 1 |
| Drug Prices: | Drug price information for BOTOX COSMETIC |
| Recent Clinical Trials: | See clinical trials for BOTOX COSMETIC |
Recent Clinical Trials for BOTOX COSMETIC
Identify potential brand extensions & biosimilar entrants
| Sponsor | Phase |
|---|---|
| University of Florida | Phase 1/Phase 2 |
| University of Chicago | Phase 2/Phase 3 |
| Cassiopea SpA | Phase 3 |
Pharmacology for BOTOX COSMETIC
| Mechanism of Action | Acetylcholine Release Inhibitors |
| Physiological Effect | Neuromuscular Blockade |
| Established Pharmacologic Class | Acetylcholine Release Inhibitor Neuromuscular Blocker |
Note on Biologic Patents
Matching patents to biologic drugs is far more complicated than for small-molecule drugs.
DrugPatentWatch employs three methods to identify biologic patents:
- Brand-side disclosures in response to biosimilar applications
- General brand-side disclosures
- Patents from broad patent text search
These patents were identified from disclosures by the brand-side company, in response to a potential biosimilar seeking to launch. They have a high certainty of blocking biosimilar entry. The expiration dates listed are not estimates — they're expiration dates as indicated by the brand-side company.
These patents were identified from searching drug labels and other general disclosures from the brand-side company. This list may exclude some of the patents which block biosimilar launch, and some of these patents listed may not actually block biosimilar launch. The expiration dates listed for these patents are estimates, based on the grant date of the patent.
For completeness, these patents were identified by searching the patent literature for mentions of the branded or ingredient name of the drug. Some of these patents protect the original drug, whereas others may protect follow-on inventions or even inventions casually mentioning the drug. The expiration dates listed for these patents are estimates, based on the grant date of the patent.
1) High Certainty: US Patents for BOTOX COSMETIC Derived from Brand-Side Litigation
No patents found based on brand-side litigation
2) High Certainty: US Patents for BOTOX COSMETIC Derived from Company Disclosures
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Patent No. | Estimated Patent Expiration | Source |
|---|---|---|---|---|---|---|---|
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2017-07-15 | Company disclosures |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2013-12-28 | Company disclosures |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2013-12-28 | Company disclosures |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2013-12-28 | Company disclosures |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2017-07-15 | Company disclosures |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2017-07-15 | Company disclosures |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2017-07-15 | Company disclosures |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Patent No. | >Estimated Patent Expiration | >Source |
3) Low Certainty: US Patents for BOTOX COSMETIC Derived from Patent Text Search
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Patent No. | Estimated Patent Expiration | Source |
|---|---|---|---|---|---|---|---|
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2033-03-11 | Patent claims search |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2039-02-26 | Patent claims search |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2039-02-26 | Patent claims search |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2034-03-16 | Patent claims search |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2036-03-11 | Patent claims search |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2039-05-16 | Patent claims search |
| Allergan, Inc. | BOTOX COSMETIC | onabotulinumtoxina | For Injection | 103000 | ⤷ Try a Trial | 2035-12-21 | Patent claims search |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Patent No. | >Estimated Patent Expiration | >Source |
International Patents for BOTOX COSMETIC
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| Hong Kong | 1199403 | ⤷ Try a Trial |
| Japan | 2010202660 | ⤷ Try a Trial |
| European Patent Office | 1563843 | ⤷ Try a Trial |
| Japan | 2012167116 | ⤷ Try a Trial |
| Mexico | 337511 | ⤷ Try a Trial |
| Denmark | 1658858 | ⤷ Try a Trial |
| Germany | 69435243 | ⤷ Try a Trial |
| >Country | >Patent Number | >Estimated Expiration |
Supplementary Protection Certificates for BOTOX COSMETIC
| Supplementary Protection Certificate | SPC Country | SPC Expiration | SPC Description |
|---|---|---|---|
| 300654 | Netherlands | ⤷ Try a Trial | DETAILS ASSIGNMENT: VERANDERING VAN EIGENAAR(S), OVERDRACHT |
| SPC/GB13/078 | United Kingdom | ⤷ Try a Trial | PRODUCT NAME: BOTULINUM TOXIN TYPE A; REGISTERED: FI 263103-5/2012 20130116; UK PL 00426/0118 - 0061 20130904; UK PL 00426/0074 - 0139 20130904; UK PL 00426/0119 - 0047 20130904 |
| 2013/025 | Ireland | ⤷ Try a Trial | PRODUCT NAME: BOTULINUM TOXIN TYPE A; NAT REGISTRATION NO/DATE: PA0148/060/001 20130117; FIRST REGISTRATION NO/DATE: PA018/060/002 17/01/2013 IRELAND PA0148/060/003 17/01/2013 FINLAND 25162 16/01/2013 FINLAND 15424 16/01/2013 FINLAND 28146 20130116 |
| 122008000042 | Germany | ⤷ Try a Trial | PRODUCT NAME: CLOSTRIDIUM BOTULINUM NEUROTOXIN TYP A (150KD), FREI VON KOMPLEXPROTEINEN; REGISTRATION NO/DATE: 57093.00.00 20050531 |
| 122008000043 | Germany | ⤷ Try a Trial | PRODUCT NAME: CLOSTRIDIUM BOTULINUM NEUROTOXIN TYP A (150KD), FREI VON KOMPLEXPROTEINEN; REGISTRATION NO/DATE: 57093.00.00 20050531 |
| 122012000065 | Germany | ⤷ Try a Trial | PRODUCT NAME: BOTULINUMTOXIN; NAT. REGISTRATION NO/DATE: 55006.00.00 74281.00.00 80457.00.00 20110920 FIRST REGISTRATION: FRANKREICH NL 25449 NL 32017 NL 32018 20110822 |
| 509 | Finland | ⤷ Try a Trial | |
| >Supplementary Protection Certificate | >SPC Country | >SPC Expiration | >SPC Description |
