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Last Updated: June 28, 2022

Patent: 10,016,338

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Summary for Patent: 10,016,338
Title:Trilayer coated pharmaceutical packaging
Abstract: An article is described including an article surface and a coating set comprising a tie coating or layer of SiO.sub.xC.sub.y or Si(NH).sub.xC.sub.y applied to the article surface, a barrier coating or layer of SiO.sub.x, and a pH protective layer of SiO.sub.xC.sub.y or Si(NH).sub.xC.sub.y. The respective coatings or layers can be applied by chemical vapor deposition of a polysiloxane or polysilazane precursor in the presence of oxygen. Examples of such an article are a prefilled thermoplastic syringe or thermoplastic pharmaceutical vial with a coated interior portion containing a pharmaceutical preparation or other fluid with a pH of 4 to 8, alternatively 5 to 9. The barrier coating or layer prevents oxygen from penetrating into the thermoplastic syringe or vial, and the tie coating or layer and pH protective coating or layer together protect the barrier layer from the contents of the syringe or vial.
Inventor(s): Weikart; Christopher (Auburn, AL), Clark; Becky L. (Auburn, AL), Stevenson; Adam (Opelika, AL), Felts; John T. (Alameda, CA)
Assignee: SIO2 MEDICAL PRODUCTS, INC. (Auburn, AL)
Application Number:15/385,150
Patent Claims:see list of patent claims

Details for Patent 10,016,338

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Emd Serono, Inc. PERGONAL menotropins For Injection 017646 08/22/1975 See Plans and Pricing 2033-03-11
Emd Serono, Inc. PERGONAL menotropins For Injection 017646 05/20/1985 See Plans and Pricing 2033-03-11
Eli Lilly And Company HUMATROPE somatropin For Injection 019640 06/23/1987 See Plans and Pricing 2033-03-11
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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