Patent: 9,920,122

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Summary for Patent: 9,920,122

Title:	Compositions and methods to enhance the immune system
Abstract:	The invention relates to the field of molecular medicine. In particular, it relates to compositions and methods to enhance the clearance of aberrant cells, e.g. cancer cells or virus-infected cells, by the host\'s immune system. Provided is a composition comprising (i) a therapeutic compound that can trigger a host\'s immune effector cells against an aberrant cell, such as a therapeutic antibody, and (ii) at least one agent capable of reducing or preventing inhibitory signal transduction initiated via SIRPalpha.
Inventor(s):	van den Berg; Timo Kars (Amsterdam, NL)
Assignee:	Stichting Sanquin Bloedvoorziening (Amsterdam, NL)
Application Number:	15/145,365
Patent Claims:	see list of patent claims

Details for Patent 9,920,122

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genentech, Inc.	RITUXAN	rituximab	Injection	103705	11/26/1997	See Plans and Pricing	2028-04-23
Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	09/25/1998	See Plans and Pricing	2028-04-23
Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	02/10/2017	See Plans and Pricing	2028-04-23
Genzyme Corporation	CAMPATH	alemtuzumab	Injection	103948	05/07/2001	See Plans and Pricing	2028-04-23
Genzyme Corporation	LEMTRADA	alemtuzumab	Injection	103948	11/14/2014	See Plans and Pricing	2028-04-23
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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