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Last Updated: September 26, 2020

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Patent: 9,388,161

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Summary for Patent: 9,388,161
Title:Tetrahydroquinoline compositions as BET bromodomain inhibitors
Abstract: The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I: ##STR00001## wherein W, X, Y, Z, R.sup.1, R.sup.2, R.sup.5, and R.sup.8 are as described herein.
Inventor(s): Bair; Kenneth W. (Wellesley, MA), Herbertz; Torsten (Stow, MA), Kauffman; Goss S. (Ledyard, CT), Kayser-Bricker; Katherine J. (Branford, CT), Luke; George P. (Clinton, CT), Martin; Matthew W. (Arlington, MA), Millan; David S. (Watertown, MA), Schiller; Shawn E. R. (Haverhill, MA), Talbot; Adam C. (Guilford, CT)
Assignee: Forma Therapeutics, Inc. (Watertown, MA)
Application Number:14/546,775
Patent Claims:see list of patent claims

Details for Patent 9,388,161

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial Forma Therapeutics, Inc. (Watertown, MA) 2033-11-18 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Forma Therapeutics, Inc. (Watertown, MA) 2033-11-18 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Forma Therapeutics, Inc. (Watertown, MA) 2033-11-18 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Forma Therapeutics, Inc. (Watertown, MA) 2033-11-18 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial Forma Therapeutics, Inc. (Watertown, MA) 2033-11-18 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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