Last Updated: June 25, 2026

Patent: 8,859,741

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Summary for Patent: 8,859,741

Title:	Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
Abstract:	Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
Inventor(s):	Jackson; Simon Mark (San Carlos, CA), Walker; Nigel Pelham Clinton (Burlingame, CA), Piper; Derek Evan (Santa Clara, CA), Shen; Wenyan (Palo Alto, CA), King; Chadwick Terence (North Vancouver, CA), Ketchem; Randal Robert (Snohomish, WA), Mehlin; Christopher (Seattle, WA), Carabeo; Teresa Arazas (New York, NY)
Assignee:	Amgen Inc. (Thousand Oaks, CA)
Application Number:	14/261,087
Patent Claims:	see list of patent claims

Details for Patent 8,859,741

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Amgen Inc.	REPATHA	evolocumab	Injection	125522	August 27, 2015	8,859,741	2034-04-24
Amgen Inc.	REPATHA	evolocumab	Injection	125522	July 08, 2016	8,859,741	2034-04-24
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 8,859,741

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Country	Patent Number	Estimated Expiration
Argentina	068011	⤷ Start Trial
Argentina	110799	⤷ Start Trial
Australia	2008288791	⤷ Start Trial
Australia	2013203677	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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