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Last Updated: April 26, 2024

Patent: 8,007,790

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Summary for Patent: 8,007,790

Title:	Methods for treating polycystic kidney disease (PKD) or other cyst forming diseases
Abstract:	The present invention is directed to methods of treating or ameliorating an effect of a polycystic disease. More particularly, the methods include administering to a patient in need thereof an amount of a modulator of a tumor necrosis factor (TNF) pathway, which is sufficient to treat or ameliorate an effect of a polycystic disease. Methods of treating or ameliorating an effect of a polycystic kidney disease (PKD) are also provided. Methods are also provided for identifying a candidate compound that may be effective to treat or ameliorate an effect of a polycystic disease or to increase polycystin-2 (PC2) function or decrease Rab11-Family of Interacting Protein2 (FIP2) function. Further provided are methods for identifying a patient having, or who is at risk for developing, a polycystic disease or who would benefit from treatment with a TNF-alpha inhibitor.
Inventor(s):	Li; Rong (Kansas City, MO), Li; Xiaogang (Prairie Village, KS)
Assignee:	Stowers Institute for Medical Research (Kansas City, MO)
Application Number:	11/906,600
Patent Claims:	see list of patent claims

Details for Patent 8,007,790

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>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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