Last Updated: June 25, 2026

Patent: 5,626,566

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Summary for Patent: 5,626,566

Title:	Large dose pen
Abstract:	A pen shaped syringe for repetitive injection of individually set doses of a medicine from a cylinder ampoule reservoir comprises a dose setting member which may be rotated to cause a rotative movement of a dosing member and a combined rotative and axial movement of an indicator member indicating the set dose, and a piston drive member which when rotated in one direction moves the piston into the cylinder ampoule. A unidirectional coupling is established between the dosing member and the piston drive member by each member carrying a disc having surfaces with sector shaped saw teeth riding over each other when the dosing member is rotated in the dose setting direction and engaging each other when the dosing member is rotated in the opposite direction corresponding to the direction of rotation by which the piston is moved into the cylinder ampoule. A nut/screw connection is established between a syringe housing and the dose setting member, and means are provided to release the unidirectional coupling between the piston drive member and the dosing member by drawing the coupling discs away from each other.
Inventor(s):	Petersen; Lars P. K. (Gentofte, DK), Hansen; Niels-Aage B. (Havdrup, DK)
Assignee:	Novo Nordisk A/S (Bagsvaerd, DK)
Application Number:	08/211,131
Patent Claims:	see list of patent claims

Details for Patent 5,626,566

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Novo Nordisk Inc.	NOVOLIN R	insulin human	Injection	019938	June 25, 1991	⤷ Start Trial	2014-03-24
Novo Nordisk Inc.	NOVOLIN R	insulin human	Injection	019938	June 01, 2018	⤷ Start Trial	2014-03-24
Novo Nordisk Inc.	NOVOLOG	insulin aspart	Injection	020986	June 07, 2000	⤷ Start Trial	2014-03-24
Novo Nordisk Inc.	NOVOLOG	insulin aspart	Injection	020986	January 19, 2001	⤷ Start Trial	2014-03-24
Novo Nordisk Inc.	NOVOLOG	insulin aspart	Injection	020986	April 23, 2004	⤷ Start Trial	2014-03-24
Novo Nordisk Inc.	NOVOLOG	insulin aspart	Injection	020986	October 31, 2013	⤷ Start Trial	2014-03-24
Novo Nordisk Inc.	NORDITROPIN	somatropin	Injection	021148	June 20, 2000	⤷ Start Trial	2014-03-24
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 5,626,566

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Country	Patent Number	Estimated Expiration
Austria	E160946	⤷ Start Trial
Australia	2795192	⤷ Start Trial
Australia	662021	⤷ Start Trial
Canada	2119913	⤷ Start Trial
Germany	69223521	⤷ Start Trial
Denmark	0608343	⤷ Start Trial
Denmark	175491	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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