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Last Updated: April 25, 2024

Patent: 10,722,468

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Summary for Patent: 10,722,468

Title:	Compositions for stabilizing and delivering proteins
Abstract:	Compositions for stabilizing and delivering proteins and/or other bioactive agents are disclosed. The bioactive agents are embedded or encapsulated in a crystalline matrix. Typically the bioactive agents are in the form of micro- or nanoparticles. The crystalline matrix confers enhanced stability to the agents embedded therein relative to other microparticulate or nanoparticulate bioactive agents. The carriers are especially useful for stabilizing bioactive macromolecules, such as proteins.
Inventor(s):	Mathiowitz; Edith (Brookline, MA), Furtado; Stacia (Pawcatuck, CT), Egilmez; Nejat (Louisville, KY), Conway; Thomas (Hamburg, NY)
Assignee:	BROWN UNIVERSITY (Providence, RI) THERAPYX, INC. (Buffalo, NY)
Application Number:	15/503,891
Patent Claims:	see list of patent claims

Details for Patent 10,722,468

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Janssen Biotech, Inc.	REMICADE	infliximab	For Injection	103772	08/24/1998	⤷ Try a Trial	2034-08-14
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	12/31/2002	⤷ Try a Trial	2034-08-14
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	02/21/2008	⤷ Try a Trial	2034-08-14
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	04/24/2013	⤷ Try a Trial	2034-08-14
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	09/23/2014	⤷ Try a Trial	2034-08-14
Abbvie Inc.	HUMIRA	adalimumab	Injection	125057	11/23/2015	⤷ Try a Trial	2034-08-14
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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