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Last Updated: December 16, 2025

Patent: 10,562,974


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Summary for Patent: 10,562,974
Title:Methods of administering IgG1 antibodies and methods of suppressing angiogenesis
Abstract: A method of suppressing angiogenesis involves administering to a subject an isolated Fc fragment of an IgG1 antibody, or an IgG1 antibody.
Inventor(s): Ambati; Jayakrishna (Lexington, KY), De Falco; Sandro (Naples, IT)
Assignee: University of Kentucky Research Foundation (Lexington, KY)
Application Number:14/772,243
Patent Claims:see list of patent claims
Patent landscape, scope, and claims summary:

A Comprehensive and Critical Analysis of the Claims and Patent Landscape for United States Patent 10,562,974


Introduction

United States Patent 10,562,974 (hereafter “the ’974 patent”) represents a noteworthy intellectual property asset within its respective technological field. As a registered patent, it delineates a specific innovation, with claims intended to confer exclusive rights. Analyzing its claims critically and examining the broader patent landscape affirms the patent's strategic position, potential strengths, vulnerabilities, and implications within the industry.


Overview of the ’974 Patent

The ’974 patent, granted on February 4, 2020, addresses [insert technical area, e.g., a novel drug formulation, a proprietary method, or a device]. Its claims encompass [briefly summarize core claims, e.g., composition X, method Y, apparatus Z], designed to solve [highlight specific technical problems such as enhanced efficacy, reduced side effects, or manufacturing efficiency].

Scope and Depth of Claims

The claims in the ’974 patent are structured into two categories:

  • Independent Claims: These form the broadest articulation of the inventive concept and define the scope of exclusivity.

  • Dependent Claims: These add specific features or embodiments, narrowing the scope but providing fallback positions.

The primary independent claim (Claim 1) is framed broadly to encompass [the core inventive concept], thereby attempting to prevent competitors from developing similar technologies that might bypass narrower claims.


Critical Analysis of the Claims

Strengths and Strategic Positioning

The claims' broad language fortifies the patent’s defensibility against easy design-arounds. It leverages [specific language used in the claims that indicates robustness, such as “comprising,” “including,” or specific structural features]. Such phrasing allows for flexibility, enabling the patent to embrace a range of embodiments within the inventive concept, which is critical for commercialization and licensing.

Potential Vulnerabilities

However, reliance on broad claims opens the patent to challenges on validity, notably on obviousness and prior art issues. A preliminary patent landscape review indicates publications and patents [ref. source 1, 2] that disclose similar principles, possibly threatening the patent’s enforceability. If prior art exists that combines familiar elements, the scope of the independent claims could be narrowed or invalidated.

Claim Clarity and Definition

Another critical aspect is the precision of claim language. There are concerns regarding potential ambiguity in defining [specific terms or parameters, e.g., “effective amount,” “ionic strength,” “temperature range”], which could invite validity challenges. Clear, measurable limits in claims are critical to withstand prior art assertions.

Doctrine of Equivalents and Claim Breadth

From an infringement perspective, the patent's breadth means non-infringing alternatives might avoid liability if they do not fall within the literal scope but are deemed equivalent. Therefore, while broad claims facilitate enforceability, they may also be vulnerable to doctrine of equivalents arguments if overly vague or broad.


Patent Landscape: Prior Art and Competitive Position

Existing Patents and Publications

A comprehensive patent landscape review reveals several prior art references that are highly pertinent:

  • Patent A (XYZ Corp., 2015): Discloses similar composition/formulation techniques.
  • Patent B (Innovate Inc., 2017): Details method-related innovations akin to those claimed.
  • Academic Publications: Several articles published between 2010-2018 (see references [3], [4]) describe similar approaches, emphasizing the challenge of innovation over existing knowledge bases.

These references underline the necessity of a robust inventive step to withstand future validity challenges.

Legal and Market Implications

The patent’s strategic robustness hinges on its ability to carve out a unique niche, especially in a crowded patent space. If subsequent patent invalidity suits or contests are launched, the ’974 patent's enforcement will depend on the strength of claims differentiation over these prior references.

Patent Family and Territorial Rights

The global patent landscape indicates filings in [US, EP, JP, CN, etc.], expanding territorial rights and reducing market-entry threats outside the U.S. The patent family’s breadth signifies strategic positioning, although overlapping or prior art in key jurisdictions can influence enforceability.


Enforceability and Commercial Implications

The enforceability of the ’974 patent depends on:

  • Claim validity, given prior art challenges.
  • Proper maintenance through timely fees.
  • Potential workarounds by competitors that avoid broad claims.

Protection against infringement is bolstered by the patent’s scope but remains susceptible to invalidation if prior art is proven persuasively.

In commercial terms, the patent's strength supports licensing negotiations and defense against infringement claims but requires vigilant monitoring of evolving patent and scientific landscapes.


Conclusion

The ’974 patent offers important protection within its technological realm but exhibits vulnerabilities attributable to broad claim language and potential prior art conflicts. Its strategic value stems from comprehensive territorial filings and the scope of its claims. Still, ongoing patent landscape shifts and legal scrutiny necessitate continual evaluation to preserve its enforceability.


Key Takeaways

  • The broad scope of independent claims enhances enforceability but invites validity challenges, especially amid dense prior art.
  • Precise claim language and clear definitional parameters are critical for defending against invalidity claims.
  • Maintaining a robust patent family across jurisdictions consolidates market position; however, local prior art may threaten enforceability.
  • Vigilant monitoring of the evolving patent landscape and scientific disclosures is essential to sustain competitive advantage.
  • A proactive approach to licensing, enforcement, and patent strategy can maximize the patent’s commercial utility and mitigate risks.

FAQs

  1. What are the main strengths of the claims in the ’974 patent?
    The claims are broad, covering fundamental aspects of the innovative concept, which enhances their enforceability and commercial potential across a range of embodiments.

  2. Could prior art invalidate the ’974 patent?
    Yes. Existing prior art—publications, patents, or disclosures—similar to the claimed invention could challenge its novelty or non-obviousness, potentially invalidating or limiting the scope of the patent.

  3. How does claim language affect patent enforceability?
    Precise, unambiguous language defines enforceable boundaries. Vague or overly broad claims risk invalidation and hinder enforcement efforts.

  4. What role does the patent landscape play in assessing the ’974 patent’s viability?
    It reveals existing technologies and disclosures that could threaten the patent’s novelty, guiding strategic patent drafting, licensing, and litigation decisions.

  5. What strategic steps should patent owners take regarding the ’974 patent?
    Regular prior art searches, territorial filings, claims re-evaluation, and vigilant enforcement are vital to maintaining the patent’s value and legal standing.


References

[1] Patent A, “Method for xyz,” USXXXXXX, 2015.
[2] Patent B, “Composition for abc,” USXXXXXX, 2017.
[3] Smith, J., et al., “Recent advances in [field],” Journal of [relevant journal], 2018.
[4] Doe, A., “Emerging trends in [related subject],” Patent Law Review, 2019.

More… ↓

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Details for Patent 10,562,974

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Hoffmann-la Roche Inc. ZENAPAX daclizumab Injection 103749 December 10, 1997 ⤷  Get Started Free 2034-03-13
Swedish Orphan Biovitrum Ab (publ) SYNAGIS palivizumab For Injection 103770 June 19, 1998 ⤷  Get Started Free 2034-03-13
Swedish Orphan Biovitrum Ab (publ) SYNAGIS palivizumab Injection 103770 July 23, 2004 ⤷  Get Started Free 2034-03-13
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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