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Generated: September 22, 2019

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Patent: 10,231,976

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Summary for Patent: 10,231,976
Title:Methods for the use of progestogen as a glucocorticoid sensitizer
Abstract: Provided are methods and kits for administering progestogen as a glucocorticoid sensitizer to restore corticosteroid sensitivity or reverse the glucocorticoid insensitivity or enhance glucocorticoid sensitivity, in order to treat one or more glucocorticoid insensitivity related diseases or conditions. For example, these include methods for reversing the glucocorticoid insensitivity in a subject having no history of menstrual cycle-related exacerbation or allergy to self-hormones, particularly progesterone, such as premenstrual or perimenstrual deterioration in the symptoms, e.g., premenstrual worsening of atopic dermatitis or premenstrual exacerbations of asthma, and exhibiting relatively or totally refractory responses to glucocorticoid therapy, e.g., glucocorticoid resistance. The methods and kits provide for the administration of a sex hormone to the subject who is corticosteroid dependent or corticoid resistant or unresponsive or intolerant to corticosteroids.
Inventor(s): Du; Tao Tom (North Potomac, MD)
Assignee: PRAIRIE PHARMACEUTICALS LLC (Bethesda, MD)
Application Number:13/021,950
Patent Claims:see list of patent claims

Details for Patent 10,231,976

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Try a Free Trial PRAIRIE PHARMACEUTICALS LLC (Bethesda, MD) 2030-02-08 RX Orphan search
Immunex ENBREL etanercept VIAL; SUBCUTANEOUS 103795 001 1998-11-02   Try a Free Trial PRAIRIE PHARMACEUTICALS LLC (Bethesda, MD) 2030-02-08 RX Orphan search
Immunex ENBREL etanercept SYRINGE 103795 002 1998-11-02   Try a Free Trial PRAIRIE PHARMACEUTICALS LLC (Bethesda, MD) 2030-02-08 RX Orphan search
Abbvie Inc HUMIRA adalimumab SYRINGE 125057 001 2002-12-31   Try a Free Trial PRAIRIE PHARMACEUTICALS LLC (Bethesda, MD) 2030-02-08 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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