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Last Updated: February 7, 2023

Patent: 10,022,427


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Summary for Patent: 10,022,427
Title:Interferon lambda-antibody complexes
Abstract: The present invention concerns methods and compositions for forming complexes of interferon-.lamda. with an antibody or antigen-binding antibody fragment. In preferred embodiments, the interferon-.lamda. and the antibody or fragment are fusion proteins, each comprising a dimerization and docking domain (DDD) moiety from human protein kinase A or an anchor domain (AD) moiety from an A-kinase anchoring protein (AKAP). In more preferred embodiments, the interferon-antibody complex is more efficacious for treatment of cancer, asthma, Alzheimer\'s disease, multiple sclerosis or viral infection than interferon-.lamda. alone, antibody alone, or the combination of unconjugated interferon-.lamda. and antibody.
Inventor(s): Chang; Chien-Hsing (Downingtown, PA), Goldenberg; David M. (Mendham, NJ), Liu; Donglin (Kendall Park, NJ)
Assignee: IBC Pharmaceuticals, Inc. (Morris Plains, NJ)
Application Number:14/997,843
Patent Claims:see list of patent claims

Details for Patent 10,022,427

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 01/10/1978 See Plans and Pricing 2028-04-10
Genzyme Corporation CAMPATH alemtuzumab Injection 103948 05/07/2001 See Plans and Pricing 2028-04-10
Genzyme Corporation LEMTRADA alemtuzumab Injection 103948 11/14/2014 See Plans and Pricing 2028-04-10
Genzyme Corporation CAMPATH alemtuzumab Injection 103948 10/12/2004 See Plans and Pricing 2028-04-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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