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Last Updated: December 17, 2025

Claims for Patent: 11,111,229

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Summary for Patent: 11,111,229

Title:	Tetrahydroquinoline compositions as BET bromodomain inhibitors
Abstract:	The present invention relates to inhibitors of bromo and extra terminal (BET) bromodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula I:wherein W, X, Y, Z, R1, R2, R5, and R8 are as described herein.
Inventor(s):	Kenneth W. Bair, Torsten Herbertz, Goss S. Kauffman, Katherine J. KAYSER-BRICKER, George P. Luke, Matthew W. Martin, David S. MILLAN, Shawn E. R. Schiller, Adam C. TALBOT
Assignee:	Forma Therapeutics Inc
Application Number:	US16/774,515
Patent Claims:

Details for Patent 11,111,229

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Recordati Rare Diseases, Inc.	ELSPAR	asparaginase	For Injection	101063	January 10, 1978	11,111,229	2040-01-28
Genentech, Inc.	RITUXAN	rituximab	Injection	103705	November 26, 1997	11,111,229	2040-01-28
Idec Pharmaceuticals Corp.	RITUXAN	rituximab	Injection	103737	February 19, 2002	11,111,229	2040-01-28
Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	September 25, 1998	11,111,229	2040-01-28
Genentech, Inc.	HERCEPTIN	trastuzumab	For Injection	103792	February 10, 2017	11,111,229	2040-01-28
Genzyme Corporation	CAMPATH	alemtuzumab	Injection	103948	May 07, 2001	11,111,229	2040-01-28
Genzyme Corporation	LEMTRADA	alemtuzumab	Injection	103948	November 14, 2014	11,111,229	2040-01-28
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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