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Last Updated: December 18, 2025

Claims for Patent: 10,703,816


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Summary for Patent: 10,703,816
Title:M971 chimeric antigen receptors
Abstract:The invention provides a chimeric antigen receptor (CAR) comprising an antigen binding domain comprising SEQ ID NOs: 1-6, a transmembrane domain, and an intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed.
Inventor(s):Rimas J. Orentas, Ira H. Pastan, Dimiter S. Dimitrov, Crystal L. Mackall
Assignee: US Department of Health and Human Services
Application Number:US16/107,271

Details for Patent 10,703,816

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Janssen Biotech, Inc. STELARA ustekinumab Injection 125261 September 25, 2009 10,703,816 2038-08-21
Janssen Biotech, Inc. STELARA ustekinumab Injection 125261 December 30, 2009 10,703,816 2038-08-21
Kite Pharma Inc. YESCARTA axicabtagene ciloleucel Injection 125643 October 18, 2017 10,703,816 2038-08-21
Kite Pharma Inc. TECARTUS brexucabtagene autoleucel For Injection 125703 July 24, 2020 10,703,816 2038-08-21
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

International Patent Family for US Patent 10,703,816

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2014065961 ⤷  Get Started Free
United States of America 2024084008 ⤷  Get Started Free
United States of America 2024084007 ⤷  Get Started Free
United States of America 2020283522 ⤷  Get Started Free
United States of America 2019085078 ⤷  Get Started Free
United States of America 2015299317 ⤷  Get Started Free
United States of America 11807682 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration

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