Last Updated: September 24, 2026

Biologic Drugs With Established Pharmaceutical Class: Interferon beta

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Biologic Drugs With Established Pharmaceutical Class: Interferon beta

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Patent Expiration
Biogen Inc.	AVONEX	interferon beta-1a	For Injection	103628	1996-05-17	⤷ Start Trial	⤷ Start Trial
Emd Serono, Inc.	REBIF	interferon beta-1a	Injection	103780	2002-03-07	⤷ Start Trial	⤷ Start Trial
Emd Serono, Inc.	REBIF	interferon beta-1a	Injection	103780	2002-03-07	4,966,843	⤷ Start Trial
Emd Serono, Inc.	REBIF	interferon beta-1a	Injection	103780	2002-03-07	6,887,462	⤷ Start Trial
Emd Serono, Inc.	REBIF	interferon beta-1a	Injection	103780	2002-03-07	7,446,173	⤷ Start Trial
Emd Serono, Inc.	REBIF	interferon beta-1a	Injection	103780	2002-03-07	7,588,755	⤷ Start Trial
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Patent Expiration

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