Patent: 7,446,173
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Summary for Patent: 7,446,173
| Title: | Polymer conjugates of interferon beta-1A and uses |
| Abstract: | An interferon beta polypeptide comprising interferon-beta 1a coupled to a polymer containing a polyalkylene glycol moiety wherein the interferon-beta-1a and the polyalkylene glycol moiety are arranged such that the interferon-beta-1a has an enhanced activity relative to another therapeutic form of interferon beta (interferon-beta-1b) and exhibits no decrease in activity as compared to non-conjugated interferon-beta-1a. The conjugates of the invention are usefully employed in therapeutic as well as non-therapeutic, e.g., diagnostic, applications. |
| Inventor(s): | Blake Pepinsky, Laura Runkel, Margot Brickelmaier, Adrian Whitty, Paula Hochman |
| Assignee: | Biogen MA Inc |
| Application Number: | US10/802,540 |
| Patent Claims: | see list of patent claims |
Details for Patent 7,446,173
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Approval Date | Patent No. | Expiredate |
|---|---|---|---|---|---|---|---|
| Emd Serono, Inc. | REBIF | interferon beta-1a | Injection | 103780 | 7-Mar-02 | ⤷ Start Trial | 2024-03-16 |
| Emd Serono, Inc. | REBIF | interferon beta-1a | Injection | 103780 | 17-Dec-04 | ⤷ Start Trial | 2024-03-16 |
| Emd Serono, Inc. | REBIF | interferon beta-1a | Injection | 103780 | 21-Dec-12 | ⤷ Start Trial | 2024-03-16 |
| Biogen Inc. | PLEGRIDY | peginterferon beta-1a | Injection | 125499 | 15-Aug-14 | ⤷ Start Trial | 2024-03-16 |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Approval Date | >Patent No. | >Expiredate |
