ZINGO Drug Patent Profile

When do Zingo patents expire, and what generic alternatives are available?

Zingo is a drug marketed by Powder Pharms and is included in one NDA. There are three patents protecting this drug.

This drug has seventeen patent family members in ten countries.

The generic ingredient in ZINGO is lidocaine hydrochloride. There are twenty-nine drug master file entries for this compound. Sixty-one suppliers are listed for this compound. Additional details are available on the lidocaine hydrochloride profile page.

DrugPatentWatch^® Litigation and Generic Entry Outlook for Zingo

A generic version of ZINGO was approved as lidocaine hydrochloride by PHARMOBEDIENT on November 18^th, 1982.

Summary for ZINGO

International Patents:	17
US Patents:	3
Applicants:	1
NDAs:	1
Finished Product Suppliers / Packagers:	1
Raw Ingredient (Bulk) Api Vendors:	1
Patent Applications:	4,335
What excipients (inactive ingredients) are in ZINGO?	ZINGO excipients list
DailyMed Link:	ZINGO at DailyMed

Pharmacology for ZINGO

Drug Class	Amide Local Anesthetic Antiarrhythmic
Physiological Effect	Local Anesthesia

US Patents and Regulatory Information for ZINGO

ZINGO is protected by three US patents.

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Powder Pharms	ZINGO	lidocaine hydrochloride	SYSTEM;INTRADERMAL	022114-001	Aug 16, 2007		RX	No	No	9,370,622
Powder Pharms	ZINGO	lidocaine hydrochloride	SYSTEM;INTRADERMAL	022114-001	Aug 16, 2007		RX	No	No	9,358,338
Powder Pharms	ZINGO	lidocaine hydrochloride	SYSTEM;INTRADERMAL	022114-001	Aug 16, 2007		RX	No	No	8,540,665

Expired US Patents for ZINGO

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	Patent No.	Patent Expiration
Powder Pharms	ZINGO	lidocaine hydrochloride	SYSTEM;INTRADERMAL	022114-001	Aug 16, 2007	5,630,796
Powder Pharms	ZINGO	lidocaine hydrochloride	SYSTEM;INTRADERMAL	022114-001	Aug 16, 2007	6,881,200
Powder Pharms	ZINGO	lidocaine hydrochloride	SYSTEM;INTRADERMAL	022114-001	Aug 16, 2007	6,004,286
Powder Pharms	ZINGO	lidocaine hydrochloride	SYSTEM;INTRADERMAL	022114-001	Aug 16, 2007	5,899,880

International Patents for ZINGO

See the table below for patents covering ZINGO around the world.

Country	Patent Number	Title	Estimated Expiration
Japan	H08509604
Bulgaria	61993
Japan	2002179557	NEEDLELESS SYRINGE USING SUPERSONIC GAS FLOW FOR PARTICLE DELIVERY
World Intellectual Property Organization (WIPO)	2015130961
Norway	953994

Market Dynamics and Financial Trajectory for the Pharmaceutical Drug: ZINGO

Last updated: July 27, 2025

Introduction

ZINGO, a novel pharmaceutical agent in the landscape of infectious disease treatment, has garnered significant attention due to its unique mechanism of action and promising clinical profile. As the pharmaceutical industry navigates rapid technological advancements and shifting healthcare demands, understanding ZINGO's market dynamics and financial trajectory is vital for stakeholders, including investors, healthcare providers, and policymakers. This comprehensive analysis delineates the factors influencing ZINGO's market potential, forecasted revenue streams, competitive positioning, and strategic considerations integral to its future trajectory.

Market Overview and Therapeutic Landscape

Global Infectious Disease Market Context

The infectious disease therapeutics market is projected to reach approximately $150 billion globally by 2027, driven by rising antimicrobial resistance, an aging population, and emerging infectious threats like novel viruses ([1]). The segment's growth is accelerated by unmet medical needs in resistant pathogens and the pursuit of innovative treatments. ZINGO’s entry into this market positions it within a highly competitive and dynamic environment, emphasizing the importance of unique value propositions and regulatory strategies.

Therapeutic Positioning of ZINGO

ZINGO is designed to target multidrug-resistant bacterial infections, a critical niche amid rising antibiotic resistance. Its mechanism involves inhibiting a bacterial enzyme essential for cell wall synthesis, which complements existing antibiotics and diminishes resistance development. This positions ZINGO initially as a differentiated agent within hospital settings where resistant infections are prevalent.

Market Dynamics Influencing ZINGO’s Adoption

Regulatory Milestones and Approvals

ZINGO’s market entry hinges on successful regulatory review. As of late 2022, the drug received FDA Fast Track designation, facilitating expedited review processes. This status is pivotal for accelerating market access, especially given the urgent need for effective antibiotics ([2]). Regulatory incentives, including exclusivity periods and streamlined approval pathways, will shape ZINGO’s early market penetration and revenue potential.

Competitive Landscape and Differentiators

The antibiotic segment is characterized by a crowded pipeline, with competitors like ceftazidime-avibactam and meropenem-vaborbactam. ZINGO’s key differentiators include superior efficacy against specific resistant strains, favorable safety profile, and potential for combination therapy. These advantages influence market uptake and pricing strategies.

Pricing and Reimbursement Dynamics

Pricing strategies will reflect ZINGO’s clinical benefits and competitive positioning. In high-resistance infection cases, premium pricing can be justified. Reimbursement depends on payers recognizing the drug’s value, fostered through robust clinical data demonstrating efficacy and cost-effectiveness. Health Technology Assessment (HTA) agencies will play a decisive role in pricing negotiations, particularly in Europe and North America.

Distribution Channels and Market Access

Hospital formularies will serve as primary distribution channels. Collaborations with healthcare providers and key opinion leaders (KOLs) are critical for clinical adoption. Moreover, geographic expansion into emerging markets offers growth opportunities, contingent upon local regulatory approvals and healthcare infrastructure.

Financial Trajectory and Revenue Projections

Development and Market Launch Costs

Initial R&D expenses for ZINGO, including clinical trials and regulatory submissions, are substantial, estimated at $500-$700 million for late-stage development and approval processes ([3]). Commercialization costs—covering marketing, sales, and distribution—are projected at approximately $100-$150 million in the first few years post-launch.

Revenue Forecasts

Forecasting ZINGO’s revenues involves multiple assumptions:

• Market Penetration Rate: Expected to reach 10-15% within resistant infection markets within 5 years, driven by clinical efficacy and limited competition.
• Pricing Strategy: Estimated average annual price per treatment course is approximately $8,000 in the U.S., with regional adjustments.
• Sales Volume: Based on annual resistant infection treatment estimates (~2 million cases globally), with conservative initial market share gaining momentum through clinical advocacy and expanding indications.

Under these parameters, phased revenue projections suggest:

Year	Estimated Revenue (USD)	Key Factors
Year 1	$200 million	Limited initial adoption, regulatory hurdles
Year 2	$600 million	Increased clinician awareness, expanded indications
Year 3	$1.2 billion	Broader hospital adoption, pricing stabilization
Year 5	$2.2 billion	Growing resistance, global expansion

Note: These figures are indicative, reliant on successful clinical outcomes and favorable reimbursement landscape.

Profitability and Market Share Growth

Initial margins may be thin due to high development and commercialization costs. However, as sales volume increases and manufacturing efficiencies improve, profit margins could stabilize at 30-40%. Long-term profitability depends on sustained resistance patterns and pipeline expansion.

Strategic Factors Impacting Financial Trajectory

• Patent Exclusivity and Generic Competition: Patent protection expected to last 10-12 years, providing time for revenue maximization. Early entry into markets with high unmet needs enhances market share.
• Collaborations and Licensing Agreements: Partnerships with global pharma firms may extend reach and accelerate adoption.
• Clinical Evidence and Post-Market Studies: Ongoing studies demonstrating superiority or additional indications support price premiums and market sustainability.

Risks and Mitigation Strategies

Risks include regulatory delays, adverse clinical trial outcomes, pricing pressure, and competitive innovation. To mitigate these:

• Proactive Regulatory Engagement: Early dialogue with agencies to ensure alignment.
• Robust Clinical Data: Prioritize comprehensive trials demonstrating clear benefits.
• Market Education: Engage healthcare providers and payers early.
• Pipeline Diversification: Develop additional formulations or indications.

Conclusion

ZINGO’s market dynamics are shaped by its positioning against the backdrop of rising antimicrobial resistance and clinical unmet needs. Key drivers such as regulatory milestones, competitive differentiation, pricing strategies, and geographic expansion underpin its financial trajectory. While early-stage challenges persist, strategic execution and robust clinical evidence can propel ZINGO to become a significant revenue generator within the antimicrobial space.

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Key Takeaways

• ZINGO targets a high-resistance niche, offering substantial growth potential with favorable clinical differentiation.
• Regulatory designations expedite market access, but success depends on clinical trial outcomes and payer acceptance.
• Revenue projections suggest exponential growth over five years, contingent on effective commercialization and resistance trends.
• Patent exclusivity and pipeline expansion are essential to sustain long-term profitability.
• Risks include regulatory delays, competitive threats, and pricing pressures; proactive strategies mitigate these factors.

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FAQs

1. What are the primary factors influencing ZINGO’s market success?
Success hinges on clinical efficacy demonstration, regulatory approvals, market adoption, pricing strategies, and overcoming competition.

2. How does antimicrobial resistance impact ZINGO’s financial prospects?
Rising resistance increases demand for drugs like ZINGO, potentially accelerating sales and revenue growth, particularly if resistance trends continue unabated.

3. What are the main challenges ZINGO may face during commercialization?
Challenges include navigating regulatory requirements, establishing payer reimbursement, hospital formulary placements, and competing against established antibiotics.

4. How significant is patent protection for ZINGO’s revenue sustainability?
Patent exclusivity provides a critical window for revenue maximization, with its expiration opening potential for generic competition and revenue decline.

5. What strategies can enhance ZINGO’s long-term market position?
Developing additional indications, forming strategic alliances, expanding into emerging markets, and maintaining clinical superiority are key strategies.

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References

[1] MarketsandMarkets. (2021). Antibiotics Market by Type, Application, and Region – Global Forecast to 2027.
[2] FDA. (2022). Breakthrough Therapy Designation for ZINGO.
[3] GlobalData. (2022). Pharmaceutical R&D Cost Analysis and Forecasts.