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Serving hundreds of leading biopharmaceutical companies globally:

Express Scripts
QuintilesIMS
Chubb
Dow
Citi
Merck
Cipla
Johnson and Johnson
Harvard Business School

Generated: May 24, 2018

DrugPatentWatch Database Preview

YONDELIS Drug Profile

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Which patents cover Yondelis, and what generic alternatives are available?

Yondelis is a drug marketed by Janssen Prods and is included in one NDA. There is one patent protecting this drug.

This drug has forty-two patent family members in thirty-five countries.

The generic ingredient in YONDELIS is trabectedin. There are four drug master file entries for this compound. One supplier is listed for this compound. Additional details are available on the trabectedin profile page.
Summary for YONDELIS
International Patents:42
US Patents:1
Applicants:1
NDAs:1
Suppliers / Packagers: 1
Bulk Api Vendors: 21
Clinical Trials: 41
Patent Applications: 10
DailyMed Link:YONDELIS at DailyMed
Drug patent expirations by year for YONDELIS
Pharmacology for YONDELIS
Drug ClassAlkylating Drug
Mechanism of ActionAlkylating Activity
Synonyms for YONDELIS
(1'R,6R,6aR,7R,13S,14S,16R)-6',8,14-Trihydroxy-7',9-dimethoxy-4,10,23-trimethyl-19-oxo-3',4',6,7,12,13,14,16-octahydrospiro(6,16-(epithiopropanooxymethano)-7,13-imino-6aH-1,3-dioxolo(7,8)isoquino(3,2-b)(3)benzazocine-20,1'(2'
(1R,2R,3R,11S,12S,14R,26R)-5,6',12-trihydroxy-6,7'-dimethoxy-7,21,30-trimethyl-27-oxo-3',4'-dihydro-2'H-17,19,28-trioxa-24-thia-13,30-diazaspiro[heptacyclo[12.9.6.1;{3,11}.0;{2,13}.0;{4,9}.0;{15,23}.0;{16,20}]triacontane-26,1
(6R,6aR,7R,13S,14S,16R,20R)-6',8,14-trihydroxy-7',9-dimethoxy-4,10,23-trimethyl-19-oxo-3',4',6,7,12,13,14,16-octahydro-2'H,6aH-spiro[7,13-epimino-6,16-(epithiopropanooxymethano)[1,3]dioxolo[7,8]isoquinolino[3,2-b][3]benzazoci
114899-77-3
87541-EP2298780A1
87541-EP2305689A1
AC-27767
AC1L33FK
AKOS025401985
AN-5365
C39H43N3O11S
CAS-114899-77-3
CCRIS 8133
CHEBI:84050
CHEMBL450449
CS-1608
D03RTK
DB05109
DSSTox_CID_26880
DSSTox_GSID_46880
DSSTox_RID_81984
DTXSID2046880
Ect 743
Ecteinascidin
ecteinascidin 743
Ecteinascidin 743;ET-743;Ecteinascidin
Ecteinascidin 743|||ET-743|||Yondelis|||NSC-684766
Ecteinascidin-743
ecteinascidine
Ecteinascidine 743
Et 743
ET-743
ET743
GTPL2774
HY-50936
ID0YZQ2TCP
LS-146121
NCGC00181159-01
NCGC00181159-02
NSC 648766
NSC 684766
NSC-684766
PKVRCIRHQMSYJX-AIFWHQITSA-N
SCHEMBL12119916
Spiro(6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo(7,8)isoquino(3,2,-b)(3)benzazocine-20,1'(2'H)-isoquinolin)-19-one, 3',4',6,6a,7,13,14,16-octahydro-5-(acetyloxy)-6',8,14-trihydroxy-7',9-dimethoxy-4,10,23-trimet
Spiro(6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo(7,8)isoquino(3,2,-b)(3)benzazocine-20,1'(2'H)-isoquinolin)-19-one, 5-(acetyloxy)-3',4',6,6a,7,13,14,16-octahydro-6',8,14-trihydroxy-7',9-dimethoxy-4,10,23-trimet
Tox21_112762
Tox21_113236
Trabectedin
Trabectedin [INN]
Trabectedin [USAN:INN:BAN]
UNII-ID0YZQ2TCP
X5006
Yondelis (TN)
Z-3121
ZINC150338708

US Patents and Regulatory Information for YONDELIS

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Janssen Prods YONDELIS trabectedin POWDER;IV (INFUSION) 207953-001 Oct 23, 2015 RX Yes Yes ➤ Sign Up ➤ Sign Up Y ➤ Sign Up
Janssen Prods YONDELIS trabectedin POWDER;IV (INFUSION) 207953-001 Oct 23, 2015 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Janssen Prods YONDELIS trabectedin POWDER;IV (INFUSION) 207953-001 Oct 23, 2015 RX Yes Yes ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Harvard Business School
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US Army
McKesson
Cerilliant
McKinsey
Healthtrust
Deloitte
Baxter

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