Last Updated: October 1, 2026

VONJO Drug Patent Profile


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When do Vonjo patents expire, and when can generic versions of Vonjo launch?

Vonjo is a drug marketed by Sobi and is included in one NDA. There are three patents protecting this drug.

The generic ingredient in VONJO is pacritinib citrate. There is one drug master file entry for this compound. One supplier is listed for this compound. Additional details are available on the pacritinib citrate profile page.

DrugPatentWatch® Generic Entry Outlook for Vonjo

Vonjo was eligible for patent challenges on February 28, 2026.

By analyzing the patents and regulatory protections it appears that the earliest date for generic entry will be February 28, 2029. This may change due to patent challenges or generic licensing.

Indicators of Generic Entry

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Summary for VONJO
DrugPatentWatch® Estimated Loss of Exclusivity (LOE) Date for VONJO
Generic Entry Date for VONJO*:
Constraining patent/regulatory exclusivity:

TREATMENT OF ADULTS WITH INTERMEDIATE OR HIGH-RISK PRIMARY OR SECONDARY (POST-POLYCYTHEMIA VERA OR POST-ESSENTIAL THROMBOCYTHEMIA) MYELOFIBROSIS (MF) WITH A PLATELET COUNT BELOW 50 X 10^9/L

NDA:
Dosage:

CAPSULE;ORAL

*The generic entry opportunity date is the latter of the last compound-claiming patent and the last regulatory exclusivity protection. Many factors can influence early or later generic entry. This date is provided as a rough estimate of generic entry potential and should not be used as an independent source.

US Patents and Regulatory Information for VONJO

VONJO is protected by six US patents and two FDA Regulatory Exclusivities.

Based on analysis by DrugPatentWatch, the earliest date for a generic version of VONJO is ⤷  Start Trial.

This potential generic entry date is based on TREATMENT OF ADULTS WITH INTERMEDIATE OR HIGH-RISK PRIMARY OR SECONDARY (POST-POLYCYTHEMIA VERA OR POST-ESSENTIAL THROMBOCYTHEMIA) MYELOFIBROSIS (MF) WITH A PLATELET COUNT BELOW 50 X 10^9/L.

Generics may enter earlier, or later, based on new patent filings, patent extensions, patent invalidation, early generic licensing, generic entry preferences, and other factors.

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Sobi VONJO pacritinib citrate CAPSULE;ORAL 208712-001 Feb 28, 2022 RX Yes Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Sobi VONJO pacritinib citrate CAPSULE;ORAL 208712-001 Feb 28, 2022 RX Yes Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Sobi VONJO pacritinib citrate CAPSULE;ORAL 208712-001 Feb 28, 2022 RX Yes Yes ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Sobi VONJO pacritinib citrate CAPSULE;ORAL 208712-001 Feb 28, 2022 RX Yes Yes ⤷  Start Trial ⤷  Start Trial Y Y ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

International Patents for VONJO

When does loss-of-exclusivity occur for VONJO?

Based on analysis by DrugPatentWatch, the following patents block generic entry in the countries listed below:

Argentina

Patent: 4724
Estimated Expiration: ⤷  Start Trial

Patent: 4133
Estimated Expiration: ⤷  Start Trial

Australia

Patent: 09325147
Estimated Expiration: ⤷  Start Trial

Brazil

Patent: 0922736
Estimated Expiration: ⤷  Start Trial

Canada

Patent: 46058
Estimated Expiration: ⤷  Start Trial

China

Patent: 2282148
Estimated Expiration: ⤷  Start Trial

Croatia

Patent: 0150428
Estimated Expiration: ⤷  Start Trial

Denmark

Patent: 76499
Estimated Expiration: ⤷  Start Trial

European Patent Office

Patent: 76499
Patent: SEL DE CITRATE DE 11-(2-PYRROLIDIN-1-YL-ETHOXY)-14,19-DIOXA-5,7,26-TRIAZA-TETRACYCLO[19.3.1.1(2,6).1(8,12)HEPTACOSA-1(25),2(26),3,5,8,10,12(27),16,21,23-DECAENE (11-(2-PYRROLIDIN-1-YL-ETHOXY)-14,19-DIOXA-5,7,26-TRIAZA-TETRACYCLO[19.3.1.1(2,6)1(8,12)]HEPTACOSA-1(25),2(26),3,5,8,10,12(27),16,21,23-DECAENE CITRATE SALT)
Estimated Expiration: ⤷  Start Trial

Hong Kong

Patent: 61877
Estimated Expiration: ⤷  Start Trial

Israel

Patent: 9379
Patent: מלח ציטראט של 11–(2–פירולידינ–1–יל–אתוקסי)–19,14–דיאוקסא–26,7,5–טריאזא–טטראציקלו[1.1.3.19(6,2)1(12,8)]הפטאקוסא–1(25),2(26),12,10,8,5,3(27)j23,21,16–דקאן (11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6)1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27)j16,21,23-decaene citrate salt)
Estimated Expiration: ⤷  Start Trial

Japan

Patent: 69748
Estimated Expiration: ⤷  Start Trial

Patent: 12511571
Patent: 11−(2−ピロリジン−1−イル−エトキシ)−14,19−ジオキサ−5,7,26−トリアザ−テトラシクロ[19.3.1.1(2,6).1(8,12)]ヘプタコサ−1(25),2(26),3,5,8,10,12(27),16,21,23−デカエンクエン酸塩
Estimated Expiration: ⤷  Start Trial

Malaysia

Patent: 0005
Patent: 11-(2-PYRROLIDIN-1-YL-ETHOXY)-14,19-DIOXA-5,7,26-TRIAZA-TETRACYCLO(19.3.1.1(2,6).1(8,12))HEPTACOSA-1(25),2(26),3,5,8,10,12(27),16,21,23-DECAENE CITRATE SALT
Estimated Expiration: ⤷  Start Trial

Mexico

Patent: 11006206
Patent: SAL DE CITRATO DE 11-(2-PIRROLIDIN-1-IL-ETOXI)-14,19-DIOXA-5,7,26- TRIAZA-TETRACICLO[19.3.1.1(2,6).1(8,12)]HEPTACOSA-1(25),2(26),3,5 ,8,10,12(27),16,21,23-DECAENO. (11-(2-PYRROLIDIN-1-YL-ETHOXY)-14,19-DIOXA-5,7,26-TRIAZA-TETRACYC LO[19.3.1.1(2,6)1(8,12)]HEPTACOSA-1(25),2(26),3,5,8,10,12(27)J16 ,21,23-DECAENE CITRATE SALT.)
Estimated Expiration: ⤷  Start Trial

New Zealand

Patent: 3223
Patent: 11-(2-PYRROLIDIN-1-YL-ETHOXY)-14,19-DIOXA-5,7,26-TRIAZA-TETRACYCLO[19.3.1.1 (2,6).1(8, 12)]HEPTACOSA-1(25),2(26),3,5,8,10,12(27),16,21,23-DECAENE CITRATE SALT
Estimated Expiration: ⤷  Start Trial

Poland

Patent: 76499
Estimated Expiration: ⤷  Start Trial

Portugal

Patent: 76499
Estimated Expiration: ⤷  Start Trial

Russian Federation

Patent: 27970
Patent: ЦИТРАТ 11-(2-ПИРРОЛИДИН-1-ИЛ-ЭТОКСИ)-14,19-ДИОКСА-5,7,26-ТРИАЗАТЕТРАЦИКЛО[19.3.1.1(2,6).1(8,12)]ГЕПТАКОЗА-1(25),2(26),3,5,8,10,12(27),16,21,23-ДЕКАЕНА (11-(2-PYRROLIDIN-1-YL-ETHOXY)-14,19-DIOXA-5,7,26-TRIAZATETRACYCLO[19.3.1.1(2,6).1(8,12)]HEPTACOSA-1(25),2(26),3,5,8,10,12(27),16,21,23-DECAENE CITRATE)
Estimated Expiration: ⤷  Start Trial

Patent: 11126173
Patent: ЦИТРАТ 11-(2-ПИРРОЛИДИН-1-ИЛ-ЭТОКСИ)-14,19-ДИОКСА-5,7,26-ТРИАЗА-ТЕТРАЦИКЛО [19.3.1.1 (2,6).1(8,12)]ГЕПТАКОЗА-1-( 25),2( 26),3,5,8,10,12( 27),16,21,23-ДЕКАЕНА (11-(2-PYRROLIDIN-1-YL-ETHOXY)-14,19-DIOXA-5,7,26-TRIAZATETRACYCLO[19.3.1.1(2,6).1(8,12)]HEPTACOSA-1(25),2(26),3,5,8,10,12(27),16,21,23-DECAENE CITRATE)
Estimated Expiration: ⤷  Start Trial

Singapore

Patent: 1907
Patent: 11-(2-PYRROLIDIN-1-YL-ETHOXY)-14,19-DIOXA-5,7,26-TRIAZA-TETRACYCLO[19.3.1.1(2,6)1(8,12)]HEPTACOSA-1(25),2(26),3,5,8,10,12(27)J16,21,23-DECAENE CITRATE SALT
Estimated Expiration: ⤷  Start Trial

South Africa

Patent: 1104032
Patent: 11-(2-PYRROLIDIN-1-YL-ETHOXY)-14,19-DIOXA-5,7,26-TRIAZA-TETRACYCLO[19.3.1.1(2,6)1(8,12)]HEPTACOSA-1(25),2(26),3,5,8,10,12(27)J16,21,23-DECAENE CITRATE SALT
Estimated Expiration: ⤷  Start Trial

South Korea

Patent: 1729918
Estimated Expiration: ⤷  Start Trial

Patent: 110106344
Patent: 11―(2―피롤리딘―1―일―에톡시)―14,19―디옥사―5,7,26―트리아자―테트라사이클로[19.3.1.1(2,6)1(8,12)]헵타코사―1(25),2(26),3,5,8,10,12(27)J16,21,23-데카엔 시트르산염 (PYRROLIDINYLETHOXYDIOXATRIAZATETRACYCLOHEPTACOSAJDECAENE CITRATE SALT)
Estimated Expiration: ⤷  Start Trial

Spain

Patent: 36558
Estimated Expiration: ⤷  Start Trial

Taiwan

Patent: 1028426
Patent: 11-(2-pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene citrate salt
Estimated Expiration: ⤷  Start Trial

Patent: 49705
Estimated Expiration: ⤷  Start Trial

Generics may enter earlier, or later, based on new patent filings, patent extensions, patent invalidation, early generic licensing, generic entry preferences, and other factors.

See the table below for additional patents covering VONJO around the world.

Country Patent Number Title Estimated Expiration
Austria E469158 ⤷  Start Trial
Australia 2006316071 ⤷  Start Trial
Australia 2006316072 ⤷  Start Trial
Brazil PI0618552 ⤷  Start Trial
>Country >Patent Number >Title >Estimated Expiration

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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors. Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data. The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free. We do not provide individual investment advice. This service is not registered with any financial regulatory agency. The information we publish is educational only and based on our opinions plus our models. By using DrugPatentWatch you acknowledge that we do not provide personalized recommendations or advice. thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user. Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.