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Serving hundreds of leading biopharmaceutical companies globally:

US Department of Justice
Baxter
AstraZeneca
Harvard Business School
Dow
McKesson
Mallinckrodt
UBS
Cipla

Generated: April 24, 2018

DrugPatentWatch Database Preview

TOPOSAR Drug Profile

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When do Toposar patents expire, and when can generic versions of Toposar launch?

Toposar is a drug marketed by Teva Parenteral and is included in one NDA.

The generic ingredient in TOPOSAR is etoposide. There are eleven drug master file entries for this compound. Six suppliers are listed for this compound. Additional details are available on the etoposide profile page.
Drug patent expirations by year for TOPOSAR
Medical Subject Heading (MeSH) Categories for TOPOSAR
Synonyms for TOPOSAR
(-)-Etoposide
(10r,11r,15r,16s)-16-([(2r,4ar,7r,8r,8as)-7,8-dihydroxy-2-methyl-hexahydro-2h-pyrano[3,2-d][1,3]diox
(10R,11R,15R,16S)-16-([(2R,4AR,7R,8R,8AS)-7,8-DIHYDROXY-2-METHYL-HEXAHYDRO-2H-PYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY)-10-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-4,6,13-TRIOXATETRACYCLO[7.7.0.0(3,7).0(11,15)]HEXA
(10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.0;{3,7}.0;{11,15}]hexadeca-1(9),2,7-trien-12
(10R,11R,15R,16S)-16-{[(2R,4AR,6R,7R,8R,8AS)-7,8-DIHYDROXY-2-METHYL-HEXAHYDRO-2H-PYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY}-10-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-4,6,13-TRIOXATETRACYCLO[7.7.0.0(3),?.0(1)(1),(1)?]HEXADECA-1,3(7),8-TRIEN-
(10R,11R,15R,16S)-16-{[(2R,4AR,6R,7R,8R,8AS)-7,8-DIHYDROXY-2-METHYL-HEXAHYDRO-2H-PYRANO[3,2-D][1,3]DIOXIN-6-YL]OXY}-10-(4-HYDROXY-3,5-DIMETHOXYPHENYL)-4,6,13-TRIOXATETRACYCLO[7.7.0.0(3),?.0(1)(1),(1)?]HEXADECA-1(9),2,7-TRIEN-
(5R,5aR,8aR,9S)-9-(((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one
(5R,5aR,8aR,9S)-9-(((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]
(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxy-phenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-one
(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f]
(5S,5aR,8aR,9R)-5-[[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-4,4a,6,7,8,8a-hexahydropyrano[3,2-d][1,3]dioxin-6-yl]oxy]-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[6,5-f][1,3]benzodioxol-8-one
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3'',4'':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside
[1,3]benzodioxol-8-one
[1,3]dioxol-6(5aH)-one
[5R-[5?,5a?,8a?,9?(R*)]]-9-[(4,6-?-Ethylidene-?-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6-(5aH)-one
121471-01-0
13165-EP2269989A1
13165-EP2270008A1
13165-EP2270014A1
13165-EP2270018A1
13165-EP2272827A1
13165-EP2272832A1
13165-EP2275413A1
13165-EP2275420A1
13165-EP2277565A2
13165-EP2277566A2
13165-EP2277567A1
13165-EP2277568A2
13165-EP2277569A2
13165-EP2277570A2
13165-EP2277865A1
13165-EP2277876A1
13165-EP2280012A2
13165-EP2281815A1
13165-EP2287156A1
13165-EP2289892A1
13165-EP2292280A1
13165-EP2292614A1
13165-EP2292615A1
13165-EP2292617A1
13165-EP2295055A2
13165-EP2295416A2
13165-EP2295426A1
13165-EP2295427A1
13165-EP2298305A1
13165-EP2298746A1
13165-EP2298748A2
13165-EP2298764A1
13165-EP2298765A1
13165-EP2298768A1
13165-EP2298772A1
13165-EP2298778A1
13165-EP2298780A1
13165-EP2301928A1
13165-EP2301933A1
13165-EP2305640A2
13165-EP2305642A2
13165-EP2305671A1
13165-EP2305679A1
13165-EP2305689A1
13165-EP2308812A2
13165-EP2308833A2
13165-EP2308839A1
13165-EP2308855A1
13165-EP2308861A1
13165-EP2311453A1
13165-EP2311807A1
13165-EP2311808A1
13165-EP2311825A1
13165-EP2311827A1
13165-EP2311829A1
13165-EP2311840A1
13165-EP2311842A2
13165-EP2314574A1
13165-EP2316832A1
13165-EP2316833A1
13165-EP2316834A1
13165-EP2374454A1
136598-18-0
201594-04-9
33419-42-0
35317-32-9
4-Demethylepipodophyllotoxin beta-D-ethylideneglucoside
4-Demethylepipodophyllotoxin-.beta.-D-ethylideneglucoside
4-DESMETHYLEPIPODOPHYLLOTOXIN 9-(4,6-O-ETHYLIDENE)-BETA-D-GLUCOPYRANOSIDE
4'-Demethyl-epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside
4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
4'-Demethylepipodophyllotoxin ethylidene-.beta.-D-glucoside
4'-O-Demethyl-1-O-(4,6-O-ethylidene-beta-D-glucopyranosyl)epipodophyllotoxin
4''-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside)
419E420
51854-34-3
6PLQ3CP4P3
76576-58-4
9-((4,6-O-Ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-
9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4- hydroxy-3,4-dimethyloxyphenyl)furo (3',4'':6,7) naptho-(2,3-d)-1,3-dioxol-6 (5aH)-one
9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one
9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3'',4'''':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-one
A-8109
AB00438905
AB00438905_19
AB00438905-17
AB00438905-18
AB07572
AC1L1VT3
AKOS007930275
Ambap33419-42-0
BCP9000669
BDBM50127140
BPBio1_000673
BRD-K37798499-001-02-5
BRD-K37798499-001-14-0
BSPBio_000611
BT000966
C-23291
C01576
C29H32O13
CC-28332
CCG-101165
CCRIS 2392
CHEBI:4911
CHEMBL44657
CPD000112002
CS-1774
D00125
D09NIB
D0B7EB
DB00773
DEMETHY-EPIPODOPHYLLOTOXIN, ETHYLIDENE GLUCOSIDE
Demethyl Epipodophyllotoxin Ethylidine Glucoside
Demethyl EpipodophyllotoxinEthylidine Glucoside
Demethyl-epiodophyllotoxin ethylidene glucoside
Demethylepipodophyllotoxin-beta-D-ethylideneglucoside
DR003331
E0675
EBD2157958
EINECS 251-509-1
EPEG
Epipodophyllotoxin VP-16213
Epipodophyllotoxin-beta-D-ethyliden-glucoside, 4'-demethyl-
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-.beta.-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside
Epipodophyllotoxin, 4'-demethyl-, 4,6-O-ethylidene-beta-D-glucopyranoside (8CI)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-.beta.-D-glucopyranoside)
Epipodophyllotoxin, 4'-demethyl-, 9-(4,6-O-ethylidene-beta-D-glucopyranoside)
Eposide
Eposin
Eposin (TN)
Eposin, Vepesid, VP-16, Toposar, Etoposide
Etopol
Etopophos (phosphate salt)
Etopophos (TN)
etoposide
Etoposide (JP15/USP/INN)
Etoposide (JP17/USP/INN)
Etoposide (VP-16)
Etoposide (VP16)
Etoposide [USAN:INN:BAN:JAN]
Etoposide [USAN:USP:INN:BAN:JAN]
ETOPOSIDE 4'-DIHYDROGENPHOSPHATE
Etoposide for system suitability, European Pharmacopoeia (EP) Reference Standard
Etoposide, European Pharmacopoeia (EP) Reference Standard
Etoposide, synthetic, >=98%, powder
Etoposide, United States Pharmacopeia (USP) Reference Standard
Etoposido
Etoposido [INN-Spanish]
Etoposidum
Etoposidum [INN-Latin]
Etosid
EVP
EX-A1207
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one-, 9-((4,6-O-ethylidene-beta-D-glucopyranosyl)oxy)5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl), (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 9-((4,6-O-(1R)-ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 9-((4,6-O-ethylidene-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9beta(R*)))-
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 9-[[4,6-O-(1R)-ethylidene-.beta.-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR,9S)-
fytosid
GTPL6815
HMS2052N05
HMS2089F14
HMS2096O13
HMS2232L03
HSDB 6517
HY-13629
KB-308978
Lastet
LS-1214
MES-012
MFCD00869325
MLS000049957
MLS001074951
MLS001424283
MLS002153463
MLS002207239
MLS002222184
MolPort-006-069-121
NC00415
NCGC00179504-02
NK 171
NSC 141540
NSC-141540
NSC141540
PL025684
PL054350
Prestwick3_000396
s1225
SAM001246880
SBI-0051910.P002
SCHEMBL4259
SMR000112002
ST24047199
trans-Etoposide
UNII-6PLQ3CP4P3
VePesid
VePESID (TN)
Vepesid J
Vepeside
VJJPUSNTGOMMGY-MRVIYFEKSA-N
VP 16
VP 16 (pharmaceutical)
VP 16-213
VP 16213
VP-16
VP-16 (TN)
VP-16-213
ZINC3938684
Zuyeyidal

US Patents and Regulatory Information for TOPOSAR

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Teva Parenteral TOPOSAR etoposide INJECTABLE;INJECTION 074166-001 Feb 27, 1995 DISCN No No ➤ Sign Up ➤ Sign Up ➤ Sign Up
Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration

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Serving hundreds of leading biopharmaceutical companies globally:

Accenture
Queensland Health
Boehringer Ingelheim
Daiichi Sankyo
Cipla
Fuji
Merck
Farmers Insurance
Medtronic

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