Last Updated: June 18, 2026

SLO-PHYLLIN Drug Patent Profile


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When do Slo-phyllin patents expire, and when can generic versions of Slo-phyllin launch?

Slo-phyllin is a drug marketed by Sanofi Aventis Us and is included in six NDAs.

The generic ingredient in SLO-PHYLLIN is theophylline. There are thirty-six drug master file entries for this compound. Twenty-seven suppliers are listed for this compound. Additional details are available on the theophylline profile page.

DrugPatentWatch® Litigation and Generic Entry Outlook for Slo-phyllin

A generic version of SLO-PHYLLIN was approved as theophylline by RHODES PHARMS on September 1st, 1982.

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Questions you can ask:
  • What is the 5 year forecast for SLO-PHYLLIN?
  • What are the global sales for SLO-PHYLLIN?
  • What is Average Wholesale Price for SLO-PHYLLIN?
Summary for SLO-PHYLLIN
US Patents:0
Applicants:1
NDAs:6
Raw Ingredient (Bulk) Api Vendors: 1
Patent Applications: 3,330
DailyMed Link:SLO-PHYLLIN at DailyMed

US Patents and Regulatory Information for SLO-PHYLLIN

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Sanofi Aventis Us SLO-PHYLLIN theophylline CAPSULE, EXTENDED RELEASE;ORAL 085206-001 May 24, 1982 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Sanofi Aventis Us SLO-PHYLLIN theophylline SYRUP;ORAL 085187-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
Sanofi Aventis Us SLO-PHYLLIN theophylline CAPSULE, EXTENDED RELEASE;ORAL 085203-001 May 24, 1982 DISCN Yes No ⤷  Start Trial ⤷  Start Trial ⤷  Start Trial
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration
Last updated: April 23, 2026

SLO-PHYLLIN (Theophylline): Market Dynamics and Financial Trajectory

SLO-PHYLLIN is an oral theophylline product (xanthine bronchodilator) used in chronic respiratory conditions. Financial trajectory and market dynamics for a legacy, off-patent, generic-active ingredient are driven by (1) generic penetration, (2) hospital and payer formulary placement, (3) channel concentration among wholesalers and pharmacy chains, and (4) manufacturing economics for low-price, high-volume oral solids.

Because the request targets a specific branded product name (“SLO-PHYLLIN”), an investment-grade market and financial readout requires brand-level historical pricing, sales, and filings. No such product-level financial dataset is provided here.

Is there brand-level sales data for SLO-PHYLLIN?

No. Without SLO-PHYLLIN-specific sales figures (IMS/IQVIA, Circana, or payer claims aggregates), any “financial trajectory” statement would be speculative.

What market dynamics govern SLO-PHYLLIN-like theophylline brands?

Theophylline (including SLO-PHYLLIN) typically behaves as a mature, low-growth respiratory generic where brand identity matters less than drug acquisition cost and formulary status. Key dynamics:

Dynamic Mechanism Competitive impact on SLO-PHYLLIN
Generic-driven price compression Multiple generic manufacturers and pharmacy substitution drive net price down over time Brand pricing power is limited; share depends on channel contracts and pharmacy acceptance
Formulary tightening Payers prefer lower-cost alternatives within respiratory maintenance regimens Ongoing pressure to maintain preferred status through rebates or positioning
Narrow clinical role Theophylline is used in specific subpopulations and when other options are unsuitable Lower total-addressable market versus inhaled controller classes
Safety monitoring burden Drug requires therapeutic drug monitoring; toxicity risk limits easy adoption Slower uptake and higher friction versus simpler maintenance therapies
Supply chain and manufacturing economics Oral solids are mature; switching costs are low but interruptions are costly Brand performance tracks manufacturer reliability and wholesaler fill rates

How do these dynamics translate into a typical financial trajectory?

For legacy theophylline products, the common pattern is:

  • Initial maturity phase: steady unit demand with gradual erosion of branded net price as generics expand.
  • Post-generic phase: volume growth slows; brand or distributor-label SKUs often decline to a niche role.
  • Late-cycle phase: residual demand concentrates where prescribers already manage patients on theophylline and where formularies maintain historical coverage.

SLO-PHYLLIN-specific deviations from this pattern cannot be asserted without branded financial history.


What financial metrics can be modeled without SLO-PHYLLIN data?

Without brand-level revenue and price history, the only defensible “financial trajectory” discussion is at the class level. Theophylline is an older agent with persistent but limited growth potential, meaning financial outcomes usually track industry-level generic pricing and formulary positioning rather than innovation-led expansions.

What valuation drivers dominate for off-patent oral generics?

For branded/generic-adjacent respiratory or older oral products, business planning typically focuses on:

  1. Net price and rebate structure (contracting with PBMs, wholesaler tiers)
  2. Volume stability (retention of existing prescribers and managed patients)
  3. Manufacturing margin (API cost, solid oral formulation throughput, batch release stability)
  4. Switching friction (patient continuity and clinical monitoring pathways)
  5. Regulatory and quality execution (inspection outcomes, supply continuity)

These inputs determine whether SLO-PHYLLIN follows a slow decline profile, flat niche performance, or intermittent share gains from channel advantage. Brand-level identification is the limiting factor.


What patent or exclusivity dynamics affect SLO-PHYLLIN’s financial path?

SLO-PHYLLIN’s active ingredient (theophylline) is not protected by meaningful, active composition or method exclusivity in most major markets, as theophylline is a long-established compound. As a result:

  • financial trajectories are primarily governed by generic competition and regulatory/market access, not new exclusivity terms;
  • product-level upside depends more on distribution strategy and contract economics than on patent-protected differentiation.

Competitive landscape: where SLO-PHYLLIN loses and where it persists

Where SLO-PHYLLIN is structurally disadvantaged

  • Versus inhaled maintenance therapies: inhaled corticosteroid/long-acting beta-agonist and other controller options typically expand faster and face less dosing complexity.
  • Versus safer oral bronchodilation options: theophylline’s narrow therapeutic index drives monitoring practices that reduce adoption.

Where SLO-PHYLLIN can persist

  • Patient continuity: stable patients maintained on theophylline often continue therapy due to clinical monitoring routines already in place.
  • Regional contracting: wholesalers and pharmacy chains can preserve share if the product maintains favorable acquisition cost.

Channel and pricing mechanics that determine financial outcomes

How wholesalers and PBMs influence SLO-PHYLLIN economics

Theophylline oral products are heavily influenced by:

  • wholesaler acquisition cost (WAC-to-NADIR mechanics)
  • PBM formulary tiers (preferred vs non-preferred)
  • rebate aggregation tied to annual formularies

Because SLO-PHYLLIN is a branded name, its financial performance depends on whether the product competes as a rebate-driven “managed brand” or as a low-cost SKU where substitution and price are dominant.


Key Takeaways

  • SLO-PHYLLIN is a legacy theophylline oral product; market dynamics are dominated by generic penetration, formulary contracting, and manufacturing economics rather than innovation-led growth.
  • Any brand-level “financial trajectory” for SLO-PHYLLIN cannot be stated without product-specific sales and net price data.
  • Theophylline products typically follow a maturity-to-residual-niche pattern: price erodes under generic competition, while volume stabilizes only where formularies and prescriber continuity support ongoing use.

FAQs

  1. What drives demand for SLO-PHYLLIN in the US?
    Ongoing patient continuity on theophylline and formulary coverage, both constrained by the drug’s monitoring burden and safety profile.

  2. How does generic competition typically affect branded SLO-PHYLLIN-style products?
    It compresses net price through substitution and PBM/wholesaler contracting leverage, usually producing slower volume growth and declining branded profitability over time.

  3. Is theophylline growth driven by new clinical adoption?
    Adoption is limited because theophylline has a narrower clinical role than modern inhaled controllers and requires therapeutic drug monitoring.

  4. What business levers most influence profitability for legacy theophylline products?
    Net price/rebates, manufacturing margin, supply continuity, and formulary tier placement.

  5. What data would be needed to quantify SLO-PHYLLIN financial trajectory precisely?
    Brand-level historical sales units, net revenue, and net price (plus formulary and channel share).


References (APA)

[1] American Society of Health-System Pharmacists. (n.d.). Theophylline. In AHFS Drug Information.
[2] National Library of Medicine. (n.d.). Theophylline (Drug information). MedlinePlus.
[3] FDA. (n.d.). Drug approvals and databases. U.S. Food and Drug Administration.

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